Evidence map›Paper›PMID 42751415›Full record

ArticlePlastic and reconstructive surgery. Global open2026

Ultrasound-guided Minimally Invasive Correction of Postblepharoplasty Lower Eyelid Hollowing Using Hyaluronic Acid: A 5-case Series.

Kikuno Onchi, Chihiro Matsui

Abstract readCase Reports
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Kikuno OnchiFrom the Omotesando Rejuva Medical Clinic, Minato-ku, Tokyo, Japan.
Chihiro MatsuiDepartment of Plastic and Reconstructive Surgery, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lower eyelid hollowing is a challenging complication following transconjunctival blepharoplasty, particularly in Asian patients with limited midface projection. Surgical revision is often unpredictable due to fibrosis, thin skin, and compromised vascularity. Minimally invasive alternatives that provide reliable contour restoration with minimal downtime are desirable. This case series includes 5 female patients presenting with persistent lower eyelid hollowing at least 3 months after transconjunctival fat removal. All patients underwent ultrasound-guided hyaluronic acid (HA) injection using a blunt cannula, with selective adhesiolysis when indicated. HA fillers were chosen based on rheological properties: VYC-17.5L for sub-orbicularis oculi fat and periosteal augmentation, and VYC-15L for periosteal and sub-orbicularis oculi muscle tear trough correction. One patient with extremely thin skin and vascular dark circles received adjunctive subcutaneous human-derived collagen. Outcomes were assessed clinically and via standardized photography at 1 and 3 months, with patient satisfaction measured using a 5-point Likert scale. All patients demonstrated visible improvement in lower eyelid contour at both follow-up visits. Patient satisfaction was high, with 4 of 5 patients reporting being very satisfied and 1 reporting being satisfied at the 3-month follow-up. Transient edema and ecchymosis occurred in 2 patients each and resolved spontaneously. No Tyndall phenomenon, vascular complications, nodules, or contour irregularities were observed. Ultrasound-guided HA injection may represent a safe and minimally invasive option for selected patients with postblepharoplasty lower eyelid hollowing, achieving favorable short-term aesthetic outcomes with high patient satisfaction.

Identifiers

PMID42751415
PMCPMC13581378

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.