Evidence map›Paper›PMID 42751397›Full record

ArticlePCN reports : psychiatry and clinical neurosciences2026

Anxious-depressive attack-A clinical state with intrusive rumination.

Hisanobu Kaiya, Takeshi Otowa, Tsukasa Sasaki, Shota Noda, Naomi Matsuda, Yojiro Sakai, Fusaka Minami

Abstract read
In one paragraph

Article in PCN reports : psychiatry and clinical neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hisanobu KaiyaPanic Disorder Research Center, Warakukai Medical Corporation Tokyo Japan.ORCID https://orcid.org/0000-0002-8701-5015
Takeshi OtowaDepartment of Psychiatry Teikyo University School of Medicine Tokyo Japan.ORCID https://orcid.org/0009-0004-5758-2870
Tsukasa SasakiLaboratory of Health Education, Graduate School of Education The University of Tokyo Tokyo Japan.
Shota NodaAkasaka Clinic, Warakukai Medical Corporation Tokyo Japan.ORCID https://orcid.org/0000-0001-7376-7630
Naomi MatsudaAkasaka Clinic, Warakukai Medical Corporation Tokyo Japan.
Yojiro SakaiYokohama Clinic, Warakukai Medical Corporation Yokohama Japan.
Fusaka MinamiPanic Disorder Research Center, Warakukai Medical Corporation Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The present study aimed to examine anxious-depressive attack (ADA) regarding its characteristics and the circumstances of onset, thereby clarifying why ADA has remained underrecognized. Methods: In this cross-sectional study, 286 psychiatric outpatients were assessed using structured clinical interviews. ADA was diagnosed according to predefined criteria, characterized by sudden and recurrent episodes beginning with intense anxious-depressive distress, followed by prolonged intrusive rumination involving negative memories or future worries and prominent negative emotions. Data on prevalence, onset, temporal patterns, phenomenology, and coping behaviors were systematically collected. Results: The lifetime prevalence of ADA was 21.7%, with onset typically during adolescence or early adulthood. Episodes most commonly occurred during periods of mental disengagement, particularly in the evening or at night, and typically lasted 2-3 h. Detailed intrusive thoughts were predominantly autobiographical, emotionally intense, and often related to temporally distant experiences. While most patients could recall the onset, offset, and content of their episodes, 43.5% regarded ADA as a mental state that anyone might experience and 29.0% had never disclosed their experiences. Maladaptive coping behaviors, including suicidal behavior or sexual derailment, were observed in 40.3% of cases. Conclusion: ADA represents a distinctive mental state preserving consciousness and memory coexist with reduced self-reflective awareness of the pathological nature of the episode. Its ego-syntonic, covert nature, prolonged duration, and relative lack of prominent somatic symptoms may contribute to underrecognition of ADA. Recognizing ADA in clinical practice should facilitate more accurate clinical assessment suggesting an appropriate treatment strategy.

Indexed as

anxious‐depressive attack (ADA)maladaptive coping behaviorsreduced self‐reflective awarenessrejection sensitivityself‐immersion

Identifiers

PMID42751397
PMCPMC13579528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.