Transient paradoxical dissociation of alveolar volume indices after single-lung transplantation in a patient with severe emphysema: A case report.

Satoshi Sagai, Mitsuko Murata, Akemi Ishii, Susumu Sato, Ichiro Sakanoue, Yumiko Saito, Miki Nagao

Abstract readCase Reports

In one paragraph

Article in Respiratory medicine case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Satoshi SagaiDepartment of Clinical Laboratory Medicine, Kyoto University Hospital, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Mitsuko MurataDepartment of Clinical Laboratory Medicine, Kyoto University Hospital, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Akemi IshiiDepartment of Clinical Laboratory Medicine, Kyoto University Hospital, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Susumu SatoDepartment of Respiratory Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Ichiro SakanoueDepartment of Thoracic Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Yumiko SaitoDepartment of Clinical Laboratory Medicine, Kyoto University Hospital, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Miki NagaoDepartment of Clinical Laboratory Medicine, Kyoto University Hospital, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measurement of the alveolar volume (VA) yields two distinct values, VA-MB and VA-SB; theoretically, the VA-MB should exceed the VA-SB. This report describes a case in which the VA-MB was less than the VA-SB following unilateral lung transplantation. After the exclusion of mechanical errors and suboptimal procedural techniques, further analysis revealed that, following unilateral lung transplantation, substantial disparities in respiratory function between the left and right lungs, as seen in severe emphysema, may trigger a physiological mechanism that reverses VA-SB and VA-MB. As a result, the pulmonary diffusing capacity of each lung may not be accurately reflected by these measurements.

Indexed as

Alveolar volumeBronchiolitis obliteransDiffusing capacityEmphysemaLung transplantation

Identifiers

PMID42751341

DOI10.1016/j.rmcr.2026.102499

PMCPMC13579458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.