Evidence map›Paper›PMID 42751070›Full record

ArticleInternational journal of nursing studies advances2026

Care of incontinence-associated dermatitis in older adults: A randomized controlled trial comparing zinc oxide-petroleum jelly and centella asiatica-aloe vera preparations.

Somphorn Chaisomsee, Samoraphop Banharak, Chakkarin Sommana, Sarunya Tuntiyasawasdikul, Supin Sim-Im, Khanisorn Ransinyo, Panita Limpawattana, Waraporn Deesui, Porntip Pimpun, Teerawat Somkamsri and 1 more

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Article in International journal of nursing studies advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Somphorn ChaisomseeNursing Department, Srinagarind Hospital, Khon Kaen University, Thailand.
Samoraphop BanharakDepartment of Gerontological Nursing, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand.
Chakkarin SommanaDepartment of Gerontological Nursing, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand.
Sarunya TuntiyasawasdikulDepartment of Pharmacognosy and toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Supin Sim-ImNursing Department, Srinagarind Hospital, Khon Kaen University, Thailand.
Khanisorn RansinyoDepartment of Gerontological Nursing, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand.
Panita LimpawattanaDepartment of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Waraporn DeesuiDepartment of Internal Medicine, Nampong Hospital, Khon Kaen University, Khon Kaen, Thailand.
Porntip PimpunNursing Department, Srinagarind Hospital, Khon Kaen University, Thailand.
Teerawat SomkamsriNursing Department, Srinagarind Hospital, Khon Kaen University, Thailand.
Orada SeeharachNursing Department, Srinagarind Hospital, Khon Kaen University, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Incontinence-associated dermatitis is common among older adults in intensive and semi-intensive care units. Impaired consciousness, incontinence, and limited self-care increase the risk of severe skin damage, negatively affecting physical, psychological, and social well-being. Aim: We compared incontinence-associated dermatitis risk, severity, skin surface pH (a measure of acidity/alkalinity), and skin moisture between the control and experimental groups. Design: Double blind block-randomized controlled trial, two groups pre-posttest design. Methods: Participants were randomly assigned to either the control or experimental group. Both participants and outcome assessors were blinded to group allocation. The control group ( Results: The two groups differed significantly ( Conclusion: A structured nursing care program combined with an herbal formulation of Centella asiatica and Aloe vera effectively reduced the risk and severity of incontinence-associated dermatitis in older adults. Furthermore, the intervention helped maintain optimal skin pH within a mildly acidic range and significantly improved and preserved skin moisture. Impact: We have provided evidence that a structured nursing care program combined with an herbal-based skin protectant (Centella asiatica and Aloe vera) effectively reduced the risk and severity of incontinence-associated dermatitis in older adults. The intervention improved key skin health indicators, including skin pH balance and moisture, supporting skin integrity and healing. These findings can inform clinical practice by guiding evidence-based incontinence-associated dermatitis prevention and management and by suggesting a cost-effective, accessible approach to improving outcomes in aging populations. Patient and Public Contribution: Patients and caregivers participated by providing informed consent and supporting intervention implementation. Nursing provided interventions to patients, and a medical doctor conducted the allergic screening and outcome verification. Clinical Trial Registration Number: TCTR20240910009 (September 10, 2024).

Indexed as

AgedIncontinenceIncontinence-associated dermatitisNursing careSkin care

Identifiers

PMID42751070
PMCPMC13579586

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.