ArticleCureus2026
Dual Intrauterine Device Placement for Refractory Endometriosis Pain in a Bicornuate Uterus: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
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Abstract
A 27-year-old nulliparous woman presented with chronic pelvic pain (CPP) (8/10 on the Numerical Rating Scale (NRS)), dysmenorrhea, heavy menstrual bleeding (HMB), and a family history of endometriosis. She had failed treatment with an etonogestrel implant and dienogest. Hysteroscopy confirmed a bicornuate uterus. Under direct hysteroscopic guidance, two levonorgestrel-releasing intrauterine systems (LNG-IUS) were inserted, with one device placed in each uterine horn. At the four-month follow-up, the patient reported a significant reduction in pain (2/10 on the NRS), dysmenorrhea, and bleeding, with ultrasound confirming correct device placement. At six months, her pain score had decreased to 1/10. Dual LNG-IUS insertion under hysteroscopic guidance represents a minimally invasive and effective strategy for managing endometriosis-related pain in patients with a bicornuate uterus when conventional therapies are inadequate. Long-term follow-up and regular monitoring are warranted to assess for potential side effects.
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