Concomitant parathyroid hormone-secreting oncocytic adrenocortical carcinoma and parathyroid adenoma.

Natalie A Moreno, Amir H Hamrahian, Christian F Meyer, Ciera Mangone, Ezra Baraban, Lilah F Morris-Wiseman

Abstract readCase Reports

In one paragraph

Article in JCEM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalie A MorenoDivision of Endocrine Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID https://orcid.org/0000-0002-5956-8288

Amir H HamrahianDivision of Endocrinology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID https://orcid.org/0000-0001-8832-9385

Christian F MeyerDivision of Oncology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID https://orcid.org/0000-0003-3329-7106

Ciera MangoneDivision of Surgical Pathology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID https://orcid.org/0009-0006-9404-6254

Ezra BarabanDivision of Surgical Pathology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Lilah F Morris-WisemanDivision of Endocrine Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID https://orcid.org/0000-0002-9751-8687

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 53-year-old man underwent resection of a nonfunctional 9 cm oncocytic adrenal cortical carcinoma (ACC) with focal high-grade features. Two years later he presented again, with gynecomastia and elevated levels of estradiol, 11-deoxycortisol, and serum calcium (10.5 mg/dL, SI: 2.62 mmol/L) (reference range 8.4-10.2 mg/dL [SI: 2.10-2.55 mmol/L]). Imaging demonstrated locally recurrent ACC, which was resected. Steroid excess resolved and he started mitotane. Months after, his calcium was 11.9 mg/dL (SI: 2.97 mmol/L), parathyroid hormone (PTH) 209 pg/mL (SI: 22.0 pmol/L) (reference range 15-65 pg/mL [SI: 1.6-6.9 pmol/L]), and parathyroid hormone-related peptide (PTHrp) was undetectable. Germline genetic testing (

Indexed as

adrenal cortical carcinomaectopic PTH secretionhypercalcemiahyperparathyroidismoncocytic adrenal tumorparathyroid

Identifiers

PMID42750903

DOI10.1210/jcemcr/luag253

PMCPMC13579050

What OpenQuestion holds

Textmetadata

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.