Evidence map›Paper›PMID 42750841›Full record

ArticleClinical case reports2026

Colon Single Stripe Sign in Chronic NSAID Use During Norovirus Infection: A Two-Hit Model of Ischemic Colitis.

Sushrut Ingawale, Rahul Kothari, Pujitha Vallivedu, Shivaji Karki, Gagandeep Singh Talwar, Jack Jacob, David Regelmann, Prabin Sharma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sushrut IngawaleFrank H. Netter MD School of Medicine Quinnipiac University, St. Vincent's Medical Center Bridgeport Connecticut USA.ORCID https://orcid.org/0000-0002-6938-6672
Rahul KothariSeth Gordhandas Sunderdas Medical College and King Edward VII Memorial Hospital Mumbai Maharashtra India.
Pujitha ValliveduFrank H. Netter MD School of Medicine Quinnipiac University, St. Vincent's Medical Center Bridgeport Connecticut USA.ORCID https://orcid.org/0000-0002-1230-1105
Shivaji KarkiInstitute of Medicine, Tribhuvan University Teaching Hospital Kathmandu Nepal.ORCID https://orcid.org/0000-0002-9111-3697
Gagandeep Singh TalwarMontgomery Family Medicine Residency Program, Baptist Health Partners Montgomery Alabama USA.
Jack JacobFrank H. Netter MD School of Medicine Quinnipiac University, St. Vincent's Medical Center Bridgeport Connecticut USA.
David RegelmannFrank H. Netter MD School of Medicine Quinnipiac University, St. Vincent's Medical Center Bridgeport Connecticut USA.
Prabin SharmaFrank H. Netter MD School of Medicine Quinnipiac University, St. Vincent's Medical Center Bridgeport Connecticut USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The colon single stripe sign (CSSS) is associated with ischemic-pattern colonic injury. We report a 69-year-old woman with norovirus infection, hematochezia, recurrent left-sided colitis, and chronic NSAID use found to have CSSS on colonoscopy, suggesting a multifactorial "two-hit" mechanism involving NSAID-related mucosal vulnerability and transient hypoperfusion.

Indexed as

abdominal painacute kidney injurycolonoscopydiarrheadrug‐related side effects and adverse reactionsgastrointestinal hemorrhageischemic colitisnon‐steroidal anti‐inflammatory agentsnorovirus

Identifiers

PMID42750841
PMCPMC13578609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.