Evidence map›Paper›PMID 42750461›Full record

ReviewJournal of microbiology and biotechnology2026

Probiotics in Cardiometabolic Diseases: Current Evidence, Postbiotic Perspectives, and Future Directions.

Fan Yang, Wanting Qin, Guoxia Zhang, Xinye Li, Xinyu Yang, Li Zhou, Yanwei Xing

Abstract readReview
In one paragraph

Review in Journal of microbiology and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fan YangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, P. R. China.
Wanting QinHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, P. R. China.
Guoxia ZhangDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, P. R. China.
Xinye LiInstitute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, P. R. China.
Xinyu YangDongfang Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, P. R. China.
Li ZhouDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, P. R. China.
Yanwei XingGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rise in urbanization and sedentary lifestyles, along with the aging of the global population, is contributing to an increasing burden of life-threatening diseases. The cardiometabolic disease (CMD) spectrum, which includes heart failure, hypertension, coronary heart disease, and diabetes, is closely associated with metabolic syndrome components such as obesity and elevated hepatic lipid accumulation. The gut microbiome mediates these disorders through multiple signaling axes. Imbalance of the intestinal microbiota is closely linked to the pathogenesis of atherosclerosis and hypertensive vascular remodeling. Supplementation with probiotics - and, more recently, their derived postbiotic products - can alter the composition and functional metabolic outputs of the gut ecosystem, offering a mechanistically informed approach for CMD management. This review delineates the mechanisms of action of six well-studied probiotics (

Indexed as

Cardiovascular DiseasesMetabolic DiseasesMetabolic SyndromeProbioticsAnimalsGastrointestinal MicrobiomeHumansPrecision MedicineAkkermansia muciniphilaCardiometabolic diseasesGut microbiome therapyPostbioticsPrecision medicineProbiotic

Identifiers

PMID42750461
PMCPMC13586607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.