Evidence map›Paper›PMID 42750396›Full record

ArticleAddiction biology2026

Mesocorticolimbic Dopamine-Reward Tract Alterations and the 'Dark Side' of Methamphetamine Addiction.

Robert J Roy, Ken T Wakabayashi, Robert J R Blair, Nicholas A Hubbard

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Addiction biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robert J RoyDepartment of Psychology, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID https://orcid.org/0000-0002-5124-7041
Ken T WakabayashiDepartment of Psychology, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Robert J R BlairDepartment of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA.
Nicholas A HubbardDepartment of Psychology, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID https://orcid.org/0000-0002-8209-4295

Funding

Rural Drug Addiction Research Center at the University of Nebraska-Lincoln
6 · The paper itself

Abstract

Mesocorticolimbic circuits are central to theories of methamphetamine and other addictions. White-matter fibres are a necessary component of those circuits. However, the extent to which mesocorticolimbic white-matter tracts are altered in methamphetamine addiction is unknown. The current study addressed this gap as well as sought to determine relationships with neurofunctional and behavioural deficits concerning nondrug rewards. Multimodal MRI was acquired from 92 people with problematic methamphetamine-use experience (MA

Indexed as

Amphetamine-Related DisordersCentral Nervous System StimulantsDopamineMethamphetamineRewardWhite MatterAdultCase-Control StudiesCorpus StriatumDiffusion Tensor ImagingFemaleHumansMagnetic Resonance ImagingMaleMesolimbic SystemNeural PathwaysCentral Nervous System StimulantsDopamineMethamphetaminedopaminemesocorticolimbicmethamphetaminereward

Identifiers

PMID42750396
PMCPMC13583458

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.