Evidence map›Paper›PMID 42749957›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Nutrition and physical activity interventions delivered to children and young people during cancer treatment: a systematic literature review.

Alexis S Ross, Émilie Bertrand, Marta Seretny, Andrea Braakhuis, Hanna van Waart, Amy L Lovell

Abstract readSystematic Review
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexis S RossDepartment of Nutrition and Dietetics, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Émilie BertrandDepartment of Nutrition and Dietetics, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Marta SeretnyTe Aka Matauranga Matepukupuku (Centre for Cancer Research, University of Auckland), Auckland, New Zealand.
Andrea BraakhuisDepartment of Nutrition and Dietetics, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Hanna van WaartTe Aka Matauranga Matepukupuku (Centre for Cancer Research, University of Auckland), Auckland, New Zealand.
Amy L LovellDepartment of Nutrition and Dietetics, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. a.lovell@auckland.ac.nz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEvaluate the evidence for nutrition and/or physical activity interventions delivered during cancer treatment and determine their efficacy.

methodsThe protocol was registered on PROSPERO (reference CRD42024513364) and completed according to the PRISMA guidelines. A comprehensive search of MEDLINE, Embase, SCOPUS, and ProQuest Health & Medical Sciences databases was conducted from inception to March 22, 2024. Risk of bias was assessed using ROB1 for randomised controlled trials, the Newcastle-Ottawa Scale for non-randomised studies, and the NIH tool for uncontrolled studies.

resultsOf the 8349 articles identified, 77 were eligible for inclusion and data extraction. These included 4 nutrition-only, 68 physical activity-only, and 4 combined nutrition and physical activity interventions. Due to significant heterogeneity in study design, variables, and outcomes, a meta-analysis was not performed. There was consistent evidence that physical activity interventions can improve exercise capacity and strength in the paediatric cancer population while benefits to physical function are inconsistent. Effective interventions utilised supervised physical activity of moderate intensity. Emerging evidence suggests that nutrition interventions can improve diet quality.

conclusionFuture prospective intervention studies should consider both nutrition and physical activity and incorporate standardised outcome measures to maximise advancements in this field.

Indexed as

ExerciseNeoplasmsAdolescentChildDietHumansChildhood cancerNutritionPhysical activity

Identifiers

PMID42749957
PMCPMC13582132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.