Evidence map›Paper›PMID 42749788›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Efficacy of transoral partial laryngectomy with zeitels and holmium laser in 42 glottic cancers.

Hongyu Wang, Ting Chen, Chenjie Hou, Zhiqiang He, Huisi Zhang, Qiaozhao Shi, Jingfang Chen, Meiying Chen

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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hongyu Wang *Department of Otolaryngology, Head and Neck Surgery, School of Clinical Medicine, Tsinghua Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, 102200, China.
Ting Chen *Department of Otolaryngology, Head and Neck Surgery, Fuzhou University Affiliated Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian Province, 350001, China. iambbp@vip.sina.com.ORCID http://orcid.org/0000-0002-1740-9529
Chenjie HouDepartment of Otolaryngology, Head and Neck Surgery, Fuzhou University Affiliated Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian Province, 350001, China.
Zhiqiang HeDepartment of Otolaryngology, Head and Neck Surgery, Fuzhou University Affiliated Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian Province, 350001, China.
Huisi ZhangDepartment of Otolaryngology, Head and Neck Surgery, Fuzhou University Affiliated Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian Province, 350001, China.
Qiaozhao ShiDepartment of Otolaryngology, Head and Neck Surgery, Fuzhou University Affiliated Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian Province, 350001, China.
Jingfang ChenDepartment of Otolaryngology, Head and Neck Surgery, Fuzhou University Affiliated Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian Province, 350001, China.
Meiying ChenDepartment of Otolaryngology, Head and Neck Surgery, Fuzhou University Affiliated Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian Province, 350001, China.

Funding

Major Scientific Research Program for Young and Middle-aged Health Professionals of Fujian Province 2022ZQNZD001
6 · The paper itself

Abstract

objectiveTo evaluate the efficacy of transoral partial laryngectomy using the suspension Zeitels laryngoscope system and holmium laser assistance (SZL-HoL) in the treatment of glottic laryngeal cancer.

methodsA retrospective analysis was conducted on 42 patients who underwent SZL-HoL and 43 patients who underwent Open Partial Laryngectomy (OPL) from January 2017 to January 2025. Patients had T1b-T2 and selected T3 glottic cancer. The study compared survival rates, intraoperative blood loss, tracheotomy rates and decannulation times, nasogastric tube placement rates and removal times, postoperative voice recovery, and hospital stay.

resultsPatients in the SZL-HoL group showed Table five-year overall survival compared with those in the OPL group (92.3% vs. 81.32%, P = 0.045), although disease-specific survival and local control did not reach statistical significance between the two groups. The SZL-HoL group also had better outcomes in terms of intraoperative blood loss, postoperative voice quality, duration of tracheotomy, duration of nasogastric tube placement, and length of hospital stay.

conclusionSZL-HoL is an effective and safe surgical approach for the treatment of T1b-T2 and selected T3 glottic cancer, offering favorable functional outcomes with acceptable oncological safety in appropriately selected patients.

Indexed as

Glottic cancerHolmium laserPrognostic evaluationSurvival rateSuspension Zeitels laryngoscope system

Identifiers

PMID42749788

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