Evidence map›Paper›PMID 42749282›Full record

ArticlePhysiologia plantarum

Epigenetic Regulation of Cotton Plant Height by Histone Acetyltransferase GhHAT11 via Hormonal Pathway Modulation.

Xin Zhang, Xingyue Zhong, Yuanxin Li, Yunhao Liusui, Wanwan Fu, Ziyu Wang, Gengqing Huang, Jingbo Zhang, Yanjun Guo, Bo Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiologia plantarum. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin ZhangXinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, College of Life Science, Xinjiang Normal University, Urumqi, China.
Xingyue ZhongXinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, College of Life Science, Xinjiang Normal University, Urumqi, China.
Yuanxin LiXinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, College of Life Science, Xinjiang Normal University, Urumqi, China.
Yunhao LiusuiXinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, College of Life Science, Xinjiang Normal University, Urumqi, China.
Wanwan FuXinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, College of Life Science, Xinjiang Normal University, Urumqi, China.
Ziyu WangXinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, College of Life Science, Xinjiang Normal University, Urumqi, China.
Gengqing HuangHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan, China.
Jingbo ZhangXinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, College of Life Science, Xinjiang Normal University, Urumqi, China.ORCID https://orcid.org/0000-0002-2843-3786
Yanjun GuoXinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, College of Life Science, Xinjiang Normal University, Urumqi, China.ORCID https://orcid.org/0000-0001-5408-2716
Bo LiXinjiang Uygur Autonomous Region Academy of Agricultural Sciences Biological Breeding Laboratory/Xinjiang Key Laboratory of Crop Biotechnology, Urumqi, China.

Funding

Doctoral Research Foundation of Xinjiang Normal University XJNUBS2215National Natural Science Foundation of China 32360489Youth Doctoral Project of the Talent Development Fund "Tianchi Youth Talent" Introduction Program in the Xinjiang Uygur Autonomous Region
6 · The paper itself

Abstract

Histone acetyltransferases (HATs) regulate transcription epigenetically through histone acetylation and play crucial roles in plant development. In this study, we identified a cotton HAT gene, GhHAT11, associated with plant height and investigated its regulatory functions and underlying mechanisms. Tissue-specific expression analysis showed that GhHAT11 was predominantly expressed in stems. Virus-induced gene silencing (VIGS) of GhHAT11 significantly reduced cotton plant height and internode cell length, whereas heterologous overexpression of GhHAT11 in Arabidopsis thaliana increased plant height, confirming its positive role in plant height regulation. Metabolomic and transcriptomic analyses revealed that silencing GhHAT11 decreased auxin and gibberellin (GA) levels, altered the expression of 3233 genes, downregulated genes involved in auxin and GA biosynthesis/signaling, and upregulated genes related to cytokinin metabolism and signaling. Furthermore, GhHAT11 positively regulates the expression of GA biosynthetic genes by maintaining H3K9ac levels at their promoters. Collectively, GhHAT11 regulates cotton plant height by coordinating gibberellin, auxin, and cytokinin pathways through modulation of hormone biosynthesis/signaling gene expression and H3K9ac-mediated control of GA biosynthetic genes.

Indexed as

Epigenesis, GeneticGossypiumHistone AcetyltransferasesPlant Growth RegulatorsPlant ProteinsArabidopsisGene Expression Regulation, PlantGibberellinsIndoleacetic AcidsPlants, Genetically ModifiedSignal TransductionGibberellinsHistone AcetyltransferasesIndoleacetic AcidsPlant Growth RegulatorsPlant ProteinscottonGAH3K9acHATsplant height

Identifiers

PMID42749282
PMCPMC13581451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.