Evidence map›Paper›PMID 42748234›Full record

ArticleScience advances2026

Structural principles underlying the evolution of SWI/SNF chromatin remodelers.

Shengsheng Ma, Mingdong Liu, Wancheng Xu, Quanmeng Wang, Xiaoman Wang, Yaoguang Huang, Muchun Li, Chihang Li, Qing-Tao Shen, Yong Chen

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shengsheng MaKey Laboratory of Epigenetic Regulation and Intervention, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.ORCID 0000-0002-3181-6171
Mingdong LiuSchool of Life Sciences, Department of Chemical Biology, Southern University of Science and Technology, Shenzhen 518055, China.ORCID 0000-0002-5321-3208
Wancheng XuKey Laboratory of Epigenetic Regulation and Intervention, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.ORCID 0000-0002-7555-4687
Quanmeng WangInstitute of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Xiaoman WangKey Laboratory of Epigenetic Regulation and Intervention, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
Yaoguang HuangKey Laboratory of Epigenetic Regulation and Intervention, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
Muchun LiKey Laboratory of Epigenetic Regulation and Intervention, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.ORCID 0009-0001-9822-3426
Chihang LiKey Laboratory of Epigenetic Regulation and Intervention, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.ORCID 0009-0004-1861-1413
Qing-Tao ShenSchool of Life Sciences, Department of Chemical Biology, Southern University of Science and Technology, Shenzhen 518055, China.ORCID 0000-0003-1672-6300
Yong ChenKey Laboratory of Epigenetic Regulation and Intervention, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.ORCID 0000-0001-5857-6086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenosine 5'-triphosphate-dependent switch/sucrose nonfermentable (SWI/SNF)-family chromatin remodelers regulate genome accessibility by repositioning nucleosomes, yet how these complexes diversified across evolution while preserving a common remodeling mechanism has remained unresolved. Here, we determine cryo-electron microscopy structures of the SWI/SNF and RSC (remodels the structure of chromatin) complexes from the thermophilic fungus

Indexed as

ChaetomiumChromatin Assembly and DisassemblyChromosomal Proteins, Non-HistoneEvolution, MolecularFungal ProteinsTranscription FactorsChromatinCryoelectron MicroscopyModels, MolecularNucleosomesChromatinChromosomal Proteins, Non-HistoneFungal ProteinsNucleosomesTranscription Factors

Identifiers

PMID42748234
PMCPMC13580576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.