Evidence map›Paper›PMID 42748135›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Bacterial stress responses lower mRNA-protein level correlations.

Sena G Süer, Jérôme Arnoux, Yi Y Lim, Ganeshwari Dhurve, Rabia Şen, Cemal Erdem, André Mateus, Kemal Avican

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sena G Süer *Department of Molecular Biology, Umeå University, Umeå 90187, Sweden.ORCID 0009-0000-0078-355X
Jérôme Arnoux *Department of Molecular Biology, Umeå University, Umeå 90187, Sweden.
Yi Y LimDepartment of Molecular Biology, Umeå University, Umeå 90187, Sweden.
Ganeshwari DhurveDepartment of Molecular Biology, Umeå University, Umeå 90187, Sweden.
Rabia ŞenScience for Life Laboratory (SciLifeLab), Umeå University, Umeå 90187, Sweden.
Cemal ErdemScience for Life Laboratory (SciLifeLab), Umeå University, Umeå 90187, Sweden.ORCID 0000-0003-3663-3646
André MateusUmeå Centre for Microbial Research (UCMR), Umeå University, Umeå 90187, Sweden.
Kemal AvicanDepartment of Molecular Biology, Umeå University, Umeå 90187, Sweden.ORCID 0000-0003-0707-2050

Funding

Kempestiftelserna (Kempe Foundations) JCK3126Knut och Alice Wallenbergs Stiftelse (kawforskning) KAW 2020.0239Vetenskapsrådet (VR) 2021-02466Vetenskapsrådet (VR) 2022-06543
6 · The paper itself

Abstract

Diverse bacterial pathogens have evolved complex regulatory mechanisms to adapt to various environmental stresses during infection. The uncertainty in mRNA-protein levels in response to environmental stressors complicates our understanding of bacterial physiology and their adaptation to stressful environments. To examine this issue, we have integrated transcriptomics and proteomics data on three human bacterial pathogens:

Indexed as

Bacterial ProteinsRNA, MessengerStress, PhysiologicalGene Expression ProfilingGene Expression Regulation, BacterialHumansOsmotic PressureProteomicsRNA, BacterialTranscriptomeBacterial ProteinsRNA, BacterialRNA, Messengerbacteriadata integrationmRNAproteinstress response

Identifiers

PMID42748135
PMCPMC13598236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.