Evidence map›Paper›PMID 42747755›Full record

ReviewDiscover nano2026

Preparation methods, mechano-bactericidal performance and mechanisms of Ti-based nanostructure arrays: A review.

Wenfang Li, Shujiao Zhang, Rui Liu, Fangchong Xing, Xingcai Guo, Lidan Zhao

Abstract readReview
In one paragraph

Review in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenfang LiSchool of Life Science and Technology, Shandong Second Medical University, Weifang, 261000, China.
Shujiao ZhangDepartment of Mechanical Engineering, Shandong Polytechnic University, Weifang, 261000, China. SJZhang_sdvcst@163.com.
Rui LiuSchool of Life Science and Technology, Shandong Second Medical University, Weifang, 261000, China.
Fangchong XingSchool of Life Science and Technology, Shandong Second Medical University, Weifang, 261000, China.
Xingcai GuoSchool of Life Science and Technology, Shandong Second Medical University, Weifang, 261000, China.
Lidan ZhaoSchool of Life Science and Technology, Shandong Second Medical University, Weifang, 261000, China. ldzhao@sdsmu.edu.cn.ORCID https://orcid.org/0000-0002-3396-950X

Funding

National Natural Science Foundation of China 32000977Natural Science Foundation of Shandong Province ZR2024QH602Natural Science Foundation of Shandong Province ZR2025MS482Natural Science Foundation of Shandong Province ZR2025QC2225ZScience and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China 2022KJ262Science and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China 2025KJH027Weifang Science and Technology Development Plan Project 2026GX048
6 · The paper itself

Abstract

Medical titanium (Ti) and its alloys have been widely employed in biomedical field, but Ti-based implants are prone to bacterial biofilm contamination, leading to implant failure. Nanostructure arrays, as a new strategy, exhibit effective bactericidal performance and biofilm inhibition only by using their own morphological characteristics, drawing extensive attention. This review mainly summarizes the progress on natural and biomimetic mechano-bactericidal nanostructure arrays, as well as the various preparation techniques for Ti-based bactericidal nanostructured surfaces, and highlights the necessity of developing controllable preparation methods. Furthermore, the critical discussion of the underlying mechano-bactericidal mechanisms is presented, identifying the need for additional experimental data to refine bacterial modeling and elucidate the complex interplay between nanostructure arrays and bacterial cells. Finally, the challenges and opportunities for Ti materials with bactericidal nanostructure arrays as implants or clinical devices are analyzed as well.

Indexed as

Bactericidal mechanismBactericidal performanceNanostructure arraysTitanium

Identifiers

PMID42747755
PMCPMC13582723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.