Evidence map›Paper›PMID 42747715›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2026

Prophylactic and therapeutic effects of aspirin in cancer.

Lizet Díaz Peralta, Erika Itayetzi Hernández Torres, Ana Isabel Burguete García, Fernando Luis Reyna Flores, Victor Hugo Bermúdez Morales

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lizet Díaz PeraltaCentro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública. Av. Universidad 655, 62100, Cuernavaca, Morelos, Mexico.
Erika Itayetzi Hernández TorresCentro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública. Av. Universidad 655, 62100, Cuernavaca, Morelos, Mexico.
Ana Isabel Burguete GarcíaCentro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública. Av. Universidad 655, 62100, Cuernavaca, Morelos, Mexico.
Fernando Luis Reyna FloresCentro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública. Av. Universidad 655, 62100, Cuernavaca, Morelos, Mexico.
Victor Hugo Bermúdez MoralesCentro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública. Av. Universidad 655, 62100, Cuernavaca, Morelos, Mexico. vbermudez@insp.mx.ORCID http://orcid.org/0000-0001-6017-4174

Funding

Instituto Nacional De Salud Pública 2013-215484.
6 · The paper itself

Abstract

Aspirin (acetylsalicylic acid) is the oldest synthetic drug and is recognized for its analgesic, antipyretic, antiplatelet effects, and mediators in inflammation. The available research evidence shows that aspirin prevents precursor lesions and cancers, and has therapeutic properties against certain cancer types. This review explores the pharmacological properties of low-dose aspirin related to its preventive effects on cancer, emphasizing the possible mechanisms of action involved in cancer control. It discusses the modulation of signaling pathways related to inflammation, regulation of the cell cycle and apoptosis, inhibition of angiogenesis associated with tumor growth, inhibition of metastasis, and regulation of the immune response. Furthermore, aspirin could be a very promising drug for adjuvant treatment in cancer patients and with implications in the prevention of certain types of cancer.

Indexed as

AnticancerAspirinProphylacticTherapeutic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.