ReviewActa biotheoretica2026
Balance Between Order and Disorder: Quantum-Epigenetic Pathways for the Emergence and Continuous Evolution of Life.
Review in Acta biotheoretica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The scientific restlessness surrounding the question of what life is (expressed in the provocations of Feynman and Schrödinger) guides this review article by integrating physics, chemistry, and biology into a multidimensional and emergent approach to the origin, evolution, and recreation of life. By exploring classical and quantum concepts, we discuss how synthetic biology, combined with epigenetics, ploidy variation, and quantum effects (such as coherence and tunneling) offers new possibilities for adapting and designing living systems. This review covers a spectrum of topics, from prebiotic chemistry experiments and the construction of protocells to practical applications in regenerative medicine, bioengineering, and astrobiology. It highlights how changes in the number of chromosome sets influence cellular plasticity and shape dynamic epigenetic environments, fostering the emergence of adaptive properties. It also explores how such factors could steer regeneration, aging, cancer development, and the expansion of life into extreme and extraplanetary environments. Based on an integrative review of scientific literature, relevant publications were selected on topics such as biological complexity, molecular organization, and adaptive strategies, with emphasis on the convergence between natural and artificial life. By considering the balance between disorder and order as a driving force of evolution, this review proposes that a deep understanding of life, anchored in a quantum-epigenetic perspective, is essential for its manipulation, restoration, and expansion. Thus, it suggests that the key to designing new forms of life lies in understanding complexity as the foundation for biotechnological innovation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.