ArticleAnnals of work exposures and health2026
Shift work, headache, and migraine in a large cohort of Dutch nurses.
Article in Annals of work exposures and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveShift work is common in healthcare and may contribute to headache disorders through mechanisms such as circadian disruption and sleep disturbance. However, evidence from large prospective cohort studies remains limited. This study investigated the associations between shift work and headache and migraine in a cohort of Dutch nurses.
methodsParticipants completed questionnaires in 2011 (n = 59,768) and 2017 (n = 37,713), reporting headache, migraine, work history, sleep problems, and lifestyle factors. Headache and migraine were assessed using the validated Headache Impact Test (HIT-6) and ID-Migraine questionnaires. Associations between shift work and the prevalence of headache or migraine at baseline and follow-up were examined using Poisson regression with robust variance to directly estimate relative risks. Additional analyses examined current shift work status and shift work duration.
resultsEver shift work was associated with a higher prevalence of headache at baseline (relative risk = 1.04, 95% confidence interval: 1.01 to 1.07), although this association attenuated after adjustment for sleep problems (relative risk = 1.01, 95% confidence interval: 0.98 to 1.04). For migraine, ever shift work was associated with a higher prevalence at follow-up (relative risk = 1.13, 95% confidence interval: 1.02 to 1.26), whereas no association was found at baseline. Current shift work was not consistently associated with headache or migraine.
conclusionsEver shift work was associated with a small increase in the prevalence of migraine. Associations with headache attenuated after adjustment for sleep problems. No consistent associations were observed for current shift work.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.