ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus-Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo-Controlled Ion Release.
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu
Abstract read
In one paragraphArticle in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
9 authors.
Bingqian WangEngineering Research Center Oral Biomaterials and Advanced Equipments, Research Center of Dental and Maxillofacial Tissue Regeneration and Repair Technology, School of Stomatology, Xi'an Medical University, Xi'an, P. R. China.ORCID https://orcid.org/0009-0009-5154-5733 Yuping ZhangEngineering Research Center Oral Biomaterials and Advanced Equipments, Research Center of Dental and Maxillofacial Tissue Regeneration and Repair Technology, School of Stomatology, Xi'an Medical University, Xi'an, P. R. China.
Xiaoning SuEngineering Research Center Oral Biomaterials and Advanced Equipments, Research Center of Dental and Maxillofacial Tissue Regeneration and Repair Technology, School of Stomatology, Xi'an Medical University, Xi'an, P. R. China.
Ning LiuEngineering Research Center Oral Biomaterials and Advanced Equipments, Research Center of Dental and Maxillofacial Tissue Regeneration and Repair Technology, School of Stomatology, Xi'an Medical University, Xi'an, P. R. China.
Hui ZengEngineering Research Center Oral Biomaterials and Advanced Equipments, Research Center of Dental and Maxillofacial Tissue Regeneration and Repair Technology, School of Stomatology, Xi'an Medical University, Xi'an, P. R. China.
Bo YangEngineering Research Center Oral Biomaterials and Advanced Equipments, Research Center of Dental and Maxillofacial Tissue Regeneration and Repair Technology, School of Stomatology, Xi'an Medical University, Xi'an, P. R. China.
Yang XueState Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an, P. R. China.ORCID https://orcid.org/0000-0002-7804-5730 Fang GuoEngineering Research Center Oral Biomaterials and Advanced Equipments, Research Center of Dental and Maxillofacial Tissue Regeneration and Repair Technology, School of Stomatology, Xi'an Medical University, Xi'an, P. R. China.
Changkui LiuEngineering Research Center Oral Biomaterials and Advanced Equipments, Research Center of Dental and Maxillofacial Tissue Regeneration and Repair Technology, School of Stomatology, Xi'an Medical University, Xi'an, P. R. China.ORCID https://orcid.org/0009-0007-6910-160X Funding
Key Research and Development Program of Shaanxi Province 2024SF-ZDCYL-01-15Special Support Program Project for Talents of Sanqin Region of Shaanxi Province 2024SQYC01Xi'an Science and Technology Bureau Project 2025JH-GXKJRC-0062Youth Innovation Team Project of Shaanxi Provincial Department of Education 24JP173
6 · The paper itselfAbstract
Titanium alloy scaffolds (Ti-6Al-4 V) are widely used to repair bone defects. However, conventional titanium-based implants lack customized functional surface interfaces that promote coordinated local nerve and blood vessel regeneration, thereby limiting bone regeneration and long-term stability. To address this limitation, we utilize a topologically optimized triple-periodic minimal surface (TPMS) porous titanium (Ti) scaffold. Polydopamine (PDA) surface engineering is used to stably immobilize europium ions (Eu
Indexed as
black phosphorus nanosheetsbone defect repaireuropiummild hyperthermia therapyneuro‐vascularizationosteogenesistriply periodic minimal surfaces
Identifiers
PMID42747145
PMCPMC13580173
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