Evidence map›Paper›PMID 42746868›Full record

ArticlePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2026

Nutrient intake and oral health outcomes in children with cow's milk allergy.

Tülin İleri, Zeynep Parlak-Hela, Gizem Erbaş Ünverdi, Ümit Murat Şahiner, Bülent Enis Şekerel, Meryem Uzamış Tekçiçek, Özge Soyer

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Article in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nutrient intake and oral health outcomes in children with cow's milk allergy.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tülin İleriFaculty of Dentistry Department of Pediatric Dentistry, Hacettepe University, Ankara, Türkiye.ORCID https://orcid.org/0000-0002-5697-3763
Zeynep Parlak-HelaFaculty of Medicine Department of Pediatric Allergy, Hacettepe University, Ankara, Türkiye.ORCID https://orcid.org/0000-0003-1247-5014
Gizem Erbaş ÜnverdiFaculty of Dentistry Department of Pediatric Dentistry, Hacettepe University, Ankara, Türkiye.
Ümit Murat ŞahinerFaculty of Medicine Department of Pediatric Allergy, Hacettepe University, Ankara, Türkiye.ORCID https://orcid.org/0000-0003-0088-913X
Bülent Enis ŞekerelFaculty of Medicine Department of Pediatric Allergy, Hacettepe University, Ankara, Türkiye.ORCID https://orcid.org/0000-0003-4232-3396
Meryem Uzamış TekçiçekFaculty of Dentistry Department of Pediatric Dentistry, Hacettepe University, Ankara, Türkiye.
Özge SoyerFaculty of Medicine Department of Pediatric Allergy, Hacettepe University, Ankara, Türkiye.ORCID https://orcid.org/0000-0002-7444-251X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral health is essential to child health, yet the impact of cow's milk allergy (CMA) is poorly defined. This study aimed to compare oral health outcomes between children with CMA and healthy controls and to identify dietary, clinical, and behavioral factors associated with these outcomes.

methodsPatients with CMA and healthy controls were examined for dental caries, gingival health, dietary habits, and oral health risk factors. A three-day food diary was used to calculate intake and cariogenic food exposure, and laboratory parameters were documented.

resultsSixty-six patients with CMA aged 2-12 years [56.1% male, median age 39.3 months, 39.4% with multiple food allergies] and 44 healthy controls [61.4% male, median age 42.5 months] were included. Dietary fat, lactose, calcium, fluoride and phosphorus intakes were lower in the CMA group, while dietary iron, vitamin D, glucose and fiber intakes were higher (p < .05). The prevalence of early childhood caries (ECC) and the presence of dmft (decayed, missing, filled primary teeth ≥ 1) were similar between the CMA and control groups (p > .05). The mean gingival index scores were elevated in the CMA group compared to the control group (0.8 ± 0.3 vs. 0.7 ± 0.4, p = .03) whereas mean plaque index scores were comparable. In the CMA group, low serum 25(OH) vitamin D was independently associated with the presence of dmft in a penalized multivariable model [aOR 4.64 (95% CI 1.29-20.59; p = .018)].

conclusionWhile no differences were observed in ECC or dmft between children with CMA and healthy controls, children with CMA had slightly higher gingival index scores. Within the CMA group, low serum 25(OH) vitamin D levels were independently associated with the presence of dmft. Oral and periodontal health monitoring may be considered as part of comprehensive, personalized care for children with CMA.

Indexed as

Dental CariesMilk HypersensitivityOral HealthAnimalsChildChild, PreschoolDietFemaleHumansMalePrevalenceRisk Factorscow's milk allergyearly childhood cariesoral health in allergic children

Identifiers

PMID42746868
PMCPMC13579604

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.