Evidence map›Paper›PMID 42746715›Full record

ArticleJournal of food science2026

Zein/Gum Arabic Nanoparticles for Cinnamaldehyde Delivery: Enhanced Antifungal Performance and Bread Shelf Life Extension.

Mônia Sartor, Vanessa Teixeira da Rosa, Laura Smaniotto Nascimento, Alisson Steffli Thill, Fabiano Bernardi, Flávio Fonseca Veras, Juliane Elisa Welke

Abstract read
In one paragraph

Article in Journal of food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mônia SartorInstitute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Vanessa Teixeira da RosaInstitute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Laura Smaniotto NascimentoInstitute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Alisson Steffli ThillGraduate Program in Physics, Institute of Physics, UFRGS, Porto Alegre, Brazil.
Fabiano BernardiGraduate Program in Physics, Institute of Physics, UFRGS, Porto Alegre, Brazil.
Flávio Fonseca VerasInstitute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Juliane Elisa WelkeInstitute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0003-0365-3683

Funding

Coordination for the Improvement of Higher Education Personnel (CAPES)Foundation for Research Support of the State of Rio Grande do Sul (FAPERGS)National Council for Scientific and Technological Development 304886/2022-0
6 · The paper itself

Abstract

Bread is highly susceptible to fungal spoilage, which limits its shelf life. The increasing interest in preservation strategies based on naturally derived antifungals is constrained by the instability of compounds such as cinnamaldehyde, the main component of cinnamon essential oil. This study evaluated cinnamaldehyde-loaded zein/gum arabic nanoparticles for bread preservation, focusing on physicochemical characterization, antifungal activity, in situ performance, and storage stability. The particles, prepared by antisolvent precipitation, showed a mean particle diameter in the nanometric range (∼255 nm), a narrow size distribution (polydispersity index < 0.2), good colloidal stability (zeta potential -21.8 mV), and suitable encapsulation efficiency (71%). Scanning electron microscopy (SEM) analyses revealed spherical particles with smooth and compact surfaces. Fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA) confirmed the incorporation of cinnamaldehyde and the enhanced stability of the compound within the polymeric matrix. Small-angle x-ray scattering (SAXS) indicated nanoscale domains consistent with cinnamaldehyde incorporation, whereas x-ray photoelectron spectroscopy (XPS) confirmed surface zein, supporting encapsulation. Encapsulation maintained or enhanced antifungal activity against Penicillium citrinum, Penicillium roqueforti, Aspergillus niger, and Aspergillus flavus, particularly at subinhibitory concentrations. In situ assays showed a marked delay in fungal growth and reduced contamination in bread treated with encapsulated cinnamaldehyde compared with the cinnamaldehyde control dispersion and untreated bread. Storage studies demonstrated that refrigeration preserved nanoparticle stability and antifungal activity for up to 180 days. Overall, zein/gum arabic nanoparticles provided a stable delivery system for cinnamaldehyde, enabling sustained antifungal performance in bread and offering a promising strategy for controlling fungal spoilage and extending shelf life.

Indexed as

AcroleinAntifungal AgentsBreadFood PreservationGum ArabicNanoparticlesZeinAspergillus flavusFood StorageParticle SizePenicilliumSpectroscopy, Fourier Transform InfraredAcroleinAntifungal AgentscinnamaldehydeGum ArabicZeinbakery productscinnamonencapsulationessential oilfungal spoilagenanocarriernanostructure

Identifiers

PMID42746715
PMCPMC13579503

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.