ArticleCell biomaterials2026
Nanoparticle-Hydrogel Composites for Precision Medicine.
Article in Cell biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Bridging Scales: Integrating Hyaluronan-Based Nanoencapsulation into 3D Hydrogel Constructs for Advanced Therapeutics-A Comprehensive Review.Gels (Basel, Switzerland) · 2026Review
- Structure-Function Engineering of Hydrogel-MOF Polymer Composites for Regenerative Wound Dressings with Emerging Antiviral Biointerface Functions.Gels (Basel, Switzerland) · 2026Review
- Hybrid Mucointeractive Delivery Systems-Alternative Approaches to Mucosal Delivery.Molecules (Basel, Switzerland) · 2026Review
- Metal Nanoparticle-Reinforced Hydrogels Applied in the Inhibition of Clinical Pathogens: Structural Features, Mechanisms, and Biomedical Prospects.Pharmaceutics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Nanoparticle-hydrogel composites hold significant potential for precision medicine. They effectively combine the molecular programming capabilities of nanoparticles and the macroscopic spatial management properties of hydrogels. This review examines the material composition of nanoparticles and hydrogels, the methods used to create composite structures, and the design elements that facilitate therapeutic customization. In theory, these systems can be engineered to target patient-specific biomarkers and coordinate multi-agent release with disease progression while adapting therapeutic dosing to individual treatment contexts that are critical for precision medicine applications. Through analysis of recent advances in cancer immunotherapy, drug delivery, gene therapy, tissue engineering, and personalized vaccination, we emphasize that clinical success demands equal focus on mechanistic sophistication along with practical considerations including manufacturing reproducibility, standardized material characterization, and evaluation frameworks that assess clinically relevant outcomes beyond traditional laboratory metrics. This review discusses the key approaches to strategically design nanoparticle-hydrogel composites to bridge the gap between preclinical studies and clinical translation in precision medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.