ArticleACG case reports journal2026
Guselkumab as a Treatment Adjunct for Pyoderma Gangrenosum While Maintaining Clinical Remission of Ulcerative Colitis.
Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis which can present as an extraintestinal manifestation of ulcerative colitis (UC). There is significant overlap in the pathophysiology of both diseases, including interleukin (IL)-23 overexpression. Guselkumab, a selective IL-23 inhibitor, has been shown to be an effective treatment option in UC and has successfully treated PG in case reports. However, there is limited literature on concomitantly treating PG and UC. We present a case in which guselkumab contributed to the treatment of PG in a patient with UC, while also maintaining clinical remission of UC.
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