ReviewOrganic chemistry frontiers : an international journal of organic chemistry2026
Eschenmoser's salts: from design to applications in organic synthesis.
Review in Organic chemistry frontiers : an international journal of organic chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
For over half a century, Eschenmoser's salt and related analogues have been widely exploited in organic synthesis, enabling the aminomethylation and α-methylenation of a broad range of substrates. Owing to their tunable structure and counterions, these salts exhibit remarkable versatility in homologation, C-C bond forming reactions, C-H functionalization, and in the synthesis of heterocycles, natural products, and biologically active compounds. This review highlights the structural modifications, reactivity, and applications of Eschenmoser-type iminium salts, emphasizing their continuing impact and adaptability in modern synthetic methodology.
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