ArticleChemical science2026
A sulfinate-azide hybrid reagent for sequential radical fluoroalkylation and click reaction.
Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A new clickable radical fluoroalkylating reagent, sodium 2-azido-1,1,2,2-tetrafluoroethanesulfinate, was prepared in one step from tetrafluoroethylene, sodium azide and sulfur dioxide. Oxidant-induced radical fluoroalkylation of arenes, heteroarenes, alkenes, and thiols, using this reagent, afforded azidotetrafluoroalkylated adducts. Their subsequent click reactions with alkynes led to
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