ArticleVeterinary medicine international2026
Evaluation of the Therapeutic Potential of Natural Peptides Against Hemagglutinin-Esterase of Bovine Coronavirus Based on Molecular Dynamics Simulation Studies.
Article in Veterinary medicine international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hemagglutinin-esterase (HE) protein of bovine coronavirus is required for virus attachment and entry into host cells. It is thus an attractive target for the development of peptide-based antiviral agents. In the present study, molecular docking was performed to identify bioactive peptides with high binding potential toward the HE protein, followed by molecular dynamics (MD) simulations. A total of 16 bioactive peptides were initially evaluated by molecular docking, and 3 peptides with favorable interactions at the HE protein functional site were subsequently subjected to MD simulations. After the simulation run, among the investigated peptides, Peptide 16 exhibited the most favorable interaction with the HE protein. Structural interaction analysis revealed the formation of two salt bridges, two hydrogen bonds, and forty hydrophobic interactions at the binding interface. Furthermore, the averaged MD analyses demonstrated that the HE protein-Peptide 16 (bLFcin
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.