Evidence map›Paper›PMID 42746348›Full record

ReviewLancet regional health. Americas2026

Acute rheumatic fever and rheumatic heart disease in Latin America: a contemporary review of epidemiology.

Antonio Mutarelli, Alexandre Negrao Pantaleao, Pilly Chillo, Dorah Nampijja, Sara Campanati, Walderez O Dutra, Maria Carmo P Nunes, Robert A Levine, Leducq PRIMA Network: Preventing Rheumatic Injury biomarker Alliance

Abstract readReview
In one paragraph

Review in Lancet regional health. Americas, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonio MutarelliSchool of Medicine, Federal University of Minas Gerais, Brazil.
Alexandre Negrao PantaleaoSchool of Medicine, Federal University of Minas Gerais, Brazil.
Pilly ChilloDepartment of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Dorah NampijjaMbarara University of Science and Technology, Mbarara, Uganda.
Sara CampanatiSchool of Medicine, Federal University of Minas Gerais, Brazil.
Walderez O DutraLaboratório Biologia das Interações Celulares, Depto. Morfologia, Instituto de Ciências Biológicas, Belo Horizonte, MG, Brazil.
Maria Carmo P NunesSchool of Medicine, Federal University of Minas Gerais, Brazil.
Robert A LevineCardiac Ultrasound Lab, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Leducq PRIMA Network: Preventing Rheumatic Injury biomarker Alliance

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatic heart disease (RHD) remains a significant public health challenge in Latin America, disproportionately affecting vulnerable populations despite global declines in disease prevalence and mortality. It is known that RHD affects over 55 million individuals worldwide, accounting for more than 390,000 deaths annually. However, region-specific RHD epidemiologic data are scarce, and most clinical studies on RHD epidemiology date back to the 1990s. On the other hand, the emergence of echocardiographic screening initiatives in the last decade reinforced the burden of the disease, revealing alarming rates of subclinical RHD in Latin American schoolchildren and young adults. This comprehensive review focused on epidemiologic data on RHD from Latin America and highlighted subgroups at highest risk for the disease.

Indexed as

Latin AmericaRheumatic FeverRheumatic heart disease

Identifiers

PMID42746348
PMCPMC13575799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.