Evidence map›Paper›PMID 42746267›Full record

ArticleChemical science2026

Remote desymmetrization of tetraoxacalix[2]arene[2]triazines enables the asymmetric synthesis of inherently chiral heteracalix[4]aromatics.

Zhanpeng Lin, Xinjie Wu, Xinyi Li, Yuanxing Kuang, Zhen Huang, Guofeng Li, Ming Zhang, Liang Hong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhanpeng LinGuangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China hongliang@sysu.edu.cn.
Xinjie WuGuangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China hongliang@sysu.edu.cn.
Xinyi LiGuangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China hongliang@sysu.edu.cn.
Yuanxing KuangGuangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China hongliang@sysu.edu.cn.
Zhen HuangGuangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China hongliang@sysu.edu.cn.
Guofeng LiSchool of Pharmacy, Shenzhen University Medical School, Shenzhen University Shenzhen 518055 China liguofeng@szu.edu.cn zhangming23@szu.edu.cn.ORCID https://orcid.org/0000-0002-7528-2036
Ming ZhangSchool of Pharmacy, Shenzhen University Medical School, Shenzhen University Shenzhen 518055 China liguofeng@szu.edu.cn zhangming23@szu.edu.cn.
Liang HongGuangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University Guangzhou 510006 China hongliang@sysu.edu.cn.ORCID https://orcid.org/0000-0002-3489-0633

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The catalytic enantioselective synthesis of inherently chiral macrocycles remains a major challenge, particularly through non-cyclization strategies. Herein, we report a chiral phosphoric acid (CPA)-catalyzed remote desymmetrization of tetraoxacalix[2]arene[2]triazines, enabling access to inherently chiral heteracalix[4]aromatics. The strategy relies on sequential S

Identifiers

PMID42746267
PMCPMC13575756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.