Evidence map›Paper›PMID 42745994›Full record

ArticleCase reports in hematology2026

Renal Outcomes Following Autologous Stem Cell Transplantation in Dialysis-Dependent Patients With Multiple Myeloma: A Single-Center Study From a Low- and Middle-Income Country.

Maher Battat, Ahmad Khursani, Mohammedkhaled J Alhendi, Momen Sawafta, Asa'd A M Daqa, Sa'ed H Zyoud, Mohanad Hassan, Hisham Asaad, Riad Amer, Ahmed Enaya

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Article in Case reports in hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maher BattatBone Marrow Transplantation and Leukemia Unit, An-Najah National University Hospital (NNUH), Nablus 44839, State of Palestine.ORCID https://orcid.org/0000-0002-7928-8013
Ahmad KhursaniBone Marrow Transplantation and Leukemia Unit, An-Najah National University Hospital (NNUH), Nablus 44839, State of Palestine.ORCID https://orcid.org/0009-0005-2701-8854
Mohammedkhaled J AlhendiDepartment of Internal Medicine, An-Najah National University Hospital, Nablus, State of Palestine, najah.edu.ORCID https://orcid.org/0009-0006-2969-4984
Momen SawaftaDepartment of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, Nablus, State of Palestine, najah.edu.ORCID https://orcid.org/0009-0001-1449-879X
Asa'd A M DaqaDepartment of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, Nablus, State of Palestine, najah.edu.ORCID https://orcid.org/0009-0008-8569-1264
Sa'ed H ZyoudDepartment of Clinical and Community Pharmacy, Faculty of Pharmacy, An-Najah National University, Nablus 44839, State of Palestine, najah.edu.ORCID https://orcid.org/0000-0002-7369-2058
Mohanad HassanDepartment of Nephrology, An-Najah National University Hospital, Nablus, State of Palestine, najah.edu.ORCID https://orcid.org/0009-0003-6150-2469
Hisham AsaadDepartment of Hematology and Oncology, An-Najah National University Hospital, Nablus, State of Palestine, najah.edu.ORCID https://orcid.org/0009-0000-8426-1336
Riad AmerDepartment of Hematology and Oncology, An-Najah National University Hospital, Nablus, State of Palestine, najah.edu.ORCID https://orcid.org/0000-0001-8806-0304
Ahmed EnayaDepartment of Nephrology, An-Najah National University Hospital, Nablus, State of Palestine, najah.edu.ORCID https://orcid.org/0000-0002-6955-1690

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Multiple myeloma (MM) frequently causes renal impairment, and a subset of patients progresses to end-stage renal disease (ESRD) requiring dialysis. Dialysis dependence has historically been considered a relative contraindication to high-dose conditioning and autologous stem cell transplantation (ASCT). Emerging evidence indicates that ASCT may provide effective hematologic control and, in selected patients, renal recovery. Methods: We conducted a retrospective case series of five dialysis-dependent patients with MM who underwent ASCT at An-Najah National University Hospital. Demographic and clinical characteristics, transplant variables, supportive-care measures, infectious and noninfectious complications, hematologic recovery, admission and discharge laboratory values, and short-term outcomes were extracted from the medical records. Results: The five patients had a mean age of 56 years and received reduced-dose melphalan (140 mg/m Conclusions: ASCT was feasible in carefully selected dialysis-dependent patients with MM and was associated with timely hematologic recovery and no 100-day treatment-related mortality. Infectious complications and vascular-access management remain major clinical concerns. Larger prospective studies are needed to define long-term renal outcomes and predictors of dialysis independence.

Indexed as

autologous stem cell transplantationcase seriesdialysis dependenceend-stage renal diseasehemodialysismultiple myelomarenal outcomes

Identifiers

PMID42745994
PMCPMC13575482

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