Evidence map›Paper›PMID 42745980›Full record

ArticleNAR genomics and bioinformatics2026

Unlocking

Tássia Mangetti Gonçalves, Casey L Stewart, Samantha D Baxley, Jason Xu, Kevin Boyer, Bijesh George, Daofeng Li, Chengran Yang, Harrison W Gabel, Xianhua Piao and 5 more

Abstract read
In one paragraph

Article in NAR genomics and bioinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tássia Mangetti GonçalvesDepartment of Genetics, Washington University School of Medicine, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0003-2929-9686
Casey L StewartDepartment of Cellular Biology, University of Georgia, Athens, GA 30602, United States.ORCID https://orcid.org/0009-0002-9409-218X
Samantha D BaxleyDepartment of Cellular Biology, University of Georgia, Athens, GA 30602, United States.
Jason XuDepartment of Computer Science, Missouri University of Science & Technology, Rolla, MO 65409, United States.
Kevin BoyerDepartment of Genetics, Washington University School of Medicine, St. Louis, MO 63110, United States.
Bijesh GeorgeDepartment of Genetics, Washington University School of Medicine, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0003-2591-5533
Daofeng LiDepartment of Genetics, Washington University School of Medicine, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0001-7492-3703
Chengran YangDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0003-4577-5590
Harrison W GabelDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, United States.
Xianhua PiaoDivision of Neonatology, Department of Pediatrics, University of California, San Francisco, CA 94143,United States.
Carlos CruchagaDepartment of Genetics, Washington University School of Medicine, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0002-5261-689X
Yang E LiDepartment of Genetics, Washington University School of Medicine, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0001-6997-6018
Ting WangDepartment of Genetics, Washington University School of Medicine, St. Louis, MO 63110, United States.
Oshri AvrahamDepartment of Cellular Biology, University of Georgia, Athens, GA 30602, United States.ORCID https://orcid.org/0000-0002-5826-0134
Guoyan ZhaoDepartment of Genetics, Washington University School of Medicine, St. Louis, MO 63110, United States.ORCID https://orcid.org/0000-0001-5615-6774

Funding

Multi-omics peripheral nerve atlas enables fine-mapping of pain molecular phenotypesU19NS130607 · NINDS · WASHINGTON UNIVERSITY · PI Robert W Gereau · 2022 to 2026
$14.0M
SIGNAL TRANSDUCTION PATHWAYS REGULATING NEURON SURVIVALR01NS041021 · NINDS · WASHINGTON UNIVERSITY · PI GABEL, HARRISON W · 2001 to 2023
$7.7M
Dissect the mechanisms of selective regional vulnerability in Lewy Body Dementias via comparative snRNA-seq analysisR01NS123571 · NINDS · WASHINGTON UNIVERSITY · PI XU, JINBIN, ZHAO, GUOYAN · 2021 to 2025
$3.6M
Optimization of imaging mass cytometry, a single-cell spatial proteomics technology, for the study of Alzheimer diseaseR21AG077643 · NIA · WASHINGTON UNIVERSITY · PI XU, JINBIN, ZHAO, GUOYAN · 2022 to 2022
$433k
Evaluating novel transcription factors in regulating astrocyte identity, reactivity, and their roles in neurodegenerative disease pathogenesisR21AG089851 · NIA · WASHINGTON UNIVERSITY · PI MUSIEK, ERIK STEVEN, ZHAO, GUOYAN · 2024 to 2024
$428k
Therapeutic targeting of DNA methyltransferases in Huntington's diseaseR21NS133823 · NINDS · WASHINGTON UNIVERSITY · PI YANO, HIROKO, ZHAO, GUOYAN · 2024 to 2025
$428k
Define molecular events driving selective neuronal death in multiple neurodegenerative diseases by snRNA-seqR03AG070474 · NIA · WASHINGTON UNIVERSITY · PI XU, JINBIN, ZHAO, GUOYAN · 2021 to 2022
$315k
NIA NIH HHS R03 AG070474NIA NIH HHS R21 AG077643NIA NIH HHS R21 AG089851NINDS NIH HHS R01 NS041021NINDS NIH HHS R01 NS123571NINDS NIH HHS R21 NS133823NINDS NIH HHS U19 NS130607
6 · The paper itself

Abstract

Genomic DNA encodes regulatory information that determines where, when, and to what extent genes are expressed. Theoretically, we should be able to identify these transcriptional "instructions" by examining genomic DNA sequence alone, yet this has remained challenging. Here we present the Vertebrate Regulatory MOdule Detector (VRMOD), a method that accurately predicts gene regulatory sequences using only the query genomic sequences. We applied VRMOD to 309 Ensembl genomes, generating a compendium of high-resolution, genome-position-fixed

Indexed as

DiseaseEvolution, MolecularRegulatory Sequences, Nucleic AcidAnimalsEnhancer Elements, GeneticGenomeHumans

Identifiers

PMID42745980
PMCPMC13575426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.