Trial reportDrug design, development and therapy2026
Effects of an Ultrasound‑Guided Femoral, Sciatic, and Genitofemoral Nerve Block with Ropivacaine on EC
Trial report in Drug design, development and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
12 authors.
Funding
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Abstract
Purpose: To determine the effective concentrations (EC Methods: Thirty-six patients scheduled for elective unilateral high saphenous vein ligation and stripping were enrolled. Nerve blocks were performed under ultrasound guidance. The effective concentration of ropivacaine was determined using the Dixon-Massey up-and-down sequential allocation method (initial concentration: 0.25%; step size: 0.01%). EC Results: Relative to baseline, hemodynamic parameters showed small but statistically significant decreases at 15 and 30 minutes after block (all P < 0.05), remaining within clinically acceptable limits. At skin incision, the VAS score in the Success group (n = 23) was significantly lower than in the Failure group (n = 13) [median (IQR), 1 (0, 2) vs 5 (4, 5); z = -5.000, P < 0.001], and the modified Bromage score was significantly higher [1 (0, 1) vs 0 (0, 0); z = -3.062, P = 0.002]. The EC Conclusion: This ultrasound-guided triple nerve block regimen is safe and effective for high saphenous vein ligation. The EC
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