ArticleFrontiers in human neuroscience2026
Altered regularity and stability of multi-finger force production in individuals with mild cognitive impairment.
Article in Frontiers in human neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
While previous studies have identified motor dysfunction in individuals with Mild Cognitive Impairment (MCI), the experimental tasks investigated to date have remained relatively limited. This study compared multi-finger force production in individuals with MCI and healthy controls (HC), employing a task designed to comprehensively reflect the complexities of neural integrity. Participants were instructed to match a target force using the net force of five fingers with real-time visual feedback, while individual finger forces were also measured. The analyses were conducted at two levels: net force level and individual finger force level. In addition, linear and non-linear approaches were utilized to examine spatial and temporal structures. At the net force level, the MCI group exhibited diminished accuracy (RMSE), increased fluctuation (CV), and lower adaptability (SampEn) in force patterns. Furthermore, the MCI group demonstrated significantly lower spatial (ΔV
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