Evidence map›Paper›PMID 42745881›Full record

ArticleFrontiers in nutrition2026

Body composition in stable COPD: associations with disease severity and early sarcopenia prediction.

Huifang Zhang, Fenkai Guo, Juanxia Chen, Huijuan Ma, Xiuhe Kang, Yuanyuan Yang, Lijun Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huifang Zhang *Department of Respiratory and Critical Care Medicine, The First People's Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, China.
Fenkai Guo *Department of Emergency Medicine, General Hospital of Ningxia Medical University, Yinchuan, China.
Juanxia ChenDepartment of Respiratory and Critical Care Medicine, The First People's Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, China.
Huijuan MaDepartment of Respiratory and Critical Care Medicine, The First People's Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, China.
Xiuhe KangDepartment of Respiratory and Critical Care Medicine, The First People's Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, China.
Yuanyuan YangDepartment of Respiratory and Critical Care Medicine, The First People's Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, China.
Lijun ChenDepartment of Respiratory and Critical Care Medicine, The First People's Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate body composition changes in patients with stable chronic obstructive pulmonary disease (COPD) and their correlation with disease severity, and to assess the value of body composition indices for early identification of concomitant sarcopenia. Methods: Patients with stable COPD were stratified according to the comprehensive disease severity assessment method in the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines, changes in body mass index (BMI), skeletal muscle index (SMI), body fat mass index (BFMI), and fat-free mass index (FFMI) were observed across groups. Factors associated with concomitant sarcopenia in COPD were analyzed, and Receiver Operating Characteristic (ROC) curves were plotted to evaluate the predictive value of the body composition indices for early screening of concomitant sarcopenia in patients with stable COPD. Results: A total of 237 patients with stable COPD (including 40 with concomitant sarcopenia) and 270 healthy controls were enrolled. In the stable COPD group, BMI, SMI, and FFMI were all positively correlated with FEV₁%pred and FEV₁/FVC (all Conclusion: Body composition alterations occur during the stable phase of COPD, especially a reduction in skeletal muscle mass. Changes in skeletal muscle indices in patients with stable COPD are significantly correlated with disease severity. Body composition analysis has potential clinical value for early identification of skeletal muscle impairment and disease assessment in stable COPD patients, and may be considered as a supplementary component of routine follow-up.

Indexed as

bioelectrical impedance analysisbody composition analysischronic obstructive pulmonary diseasesarcopeniaskeletal muscle index

Identifiers

PMID42745881
PMCPMC13574661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.