Evidence map›Paper›PMID 42745824›Full record

ArticleFrontiers in oncology2026

Metformin potentiates arsenic disulfide in diffuse large B-cell lymphoma: modulation of BAX/BCL-2 apoptotic pathway and hedgehog pathway.

Jiahao Zhang, Huawei Li, Mingxin Zhao, Chen Chen, Shenghong Du, Ling Wang

Abstract read
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiahao ZhangQingdao Medical College of Qingdao University, Qingdao, Shandong, China.
Huawei LiDepartment of Information, The Affiliated Tai'an City Central Hospital of Qingdao University, Tai'an, Shandong, China.
Mingxin ZhaoQingdao Medical College of Qingdao University, Qingdao, Shandong, China.
Chen ChenDepartment of Hematology, The Affiliated Tai'an City Central Hospital of Qingdao University, Tai'an, Shandong, China.
Shenghong DuDepartment of Hematology, The Affiliated Tai'an City Central Hospital of Qingdao University, Tai'an, Shandong, China.
Ling WangDepartment of Hematology, The Affiliated Tai'an City Central Hospital of Qingdao University, Tai'an, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Arsenic disulfide (As Methods: DLBCL cell lines (DB and SU-DHL-4) were treated with metformin and/or As Results: Both metformin and As Conclusions: Metformin enhances the anti-proliferative and pro-apoptotic effects of As

Indexed as

apoptosisarsenic disulfidediffuse large B-cell lymphomahedgehog signalingmetformin

Identifiers

PMID42745824
PMCPMC13574686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.