Evidence map›Paper›PMID 42745814›Full record

ReviewFrontiers in chemistry2026

The interactions between antimicrobial materials and bacterial membranes.

Christopher Wilde, Tzong-Hsien Lee, Ketav Kulkarni, Jhih-Hang Jiang, Anton Y Peleg, Yue Qu, Marie-Isabel Aguilar

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christopher WildeDepartment of Biochemistry & Molecular Biology, Monash University, Melbourne, VIC, Australia.
Tzong-Hsien LeeDepartment of Biochemistry & Molecular Biology, Monash University, Melbourne, VIC, Australia.
Ketav KulkarniDepartment of Biochemistry & Molecular Biology, Monash University, Melbourne, VIC, Australia.
Jhih-Hang JiangDepartment of Microbiology, Monash University, Melbourne, VIC, Australia.
Anton Y PelegDepartment of Microbiology, Monash University, Melbourne, VIC, Australia.
Yue QuDepartment of Microbiology, Monash University, Melbourne, VIC, Australia.
Marie-Isabel AguilarDepartment of Biochemistry & Molecular Biology, Monash University, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial contamination of surfaces in everyday use is an on-going challenge to prevent and eradicate. Furthermore, rapidly growing resistance of microorganisms to many drugs and disinfectants also poses a significant challenge in the design of more effective materials for managing such critical areas as food safety, aged care and agricultural, veterinary and clinical settings in general. Antimicrobial peptides (AMPs) are the primary line of defence of the innate immune system against invading microorganisms and act by binding to and disrupting the outer membranes of microbial cells. Antimicrobial biomaterials also have the potential to transform the current management of microbial contamination. Various polymer-based antimicrobial materials have been developed and many of these are designed to mimic the cationic properties of AMPs or with AMPs grafted onto a polymer template. These antibacterial materials therefore act by membrane disruption. This review provides an overview of the field of antimicrobial materials with a focus on the impact of these materials on bacterial membrane, and aim to provide a timely overview of the molecular mechanism of action of these materials.

Indexed as

antibioflimantimicrobial materialsantimicrobial pepidesbacterial membranesconjugated AMPs

Identifiers

PMID42745814
PMCPMC13574710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.