Evidence map›Paper›PMID 42745778›Full record

Trial reportFrontiers in oral health2026

Vitamin D

Sarah M Nizar Feteih, Emily L G Heaphy, Amjad Aljagthmi, Abdullah Abumdaini, Daniyah Bayumi, Ghadeer Albishi, Ashraf Dada

Abstract readClinical Trial
In one paragraph

Trial report in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah M Nizar FeteihKing Faisal Specialist Hospital and Research Centre, Department of Dentistry, Periodontology, Jeddah, Saudi Arabia.
Emily L G HeaphyKing Faisal Specialist Hospital and Research Centre, Department of Research Center, Jeddah, Saudi Arabia.
Amjad AljagthmiKing Faisal Specialist Hospital and Research Centre, Department of Research Center, Jeddah, Saudi Arabia.
Abdullah AbumdainiKing Faisal Specialist Hospital and Research Centre, Department of Pharmacy, Jeddah, Saudi Arabia.
Daniyah BayumiKing Faisal Specialist Hospital and Research Centre, Department of Pathology and Laboratory Medicine, Virology Technology, Jeddah, Saudi Arabia.
Ghadeer AlbishiKing Faisal Specialist Hospital and Research Centre, Department of Pathology and Laboratory Medicine, Virology Technology, Jeddah, Saudi Arabia.
Ashraf DadaKing Faisal Specialist Hospital and Research Centre, Department of Pathology and Laboratory Medicine, Virology Technology, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To determine whether a Vitamin D Methods: In this prospective, paired-sample, single-blind clinical trial, 25 adults with laboratory-confirmed SARS-CoV-2 infection provided saliva immediately before and after a standardized one-minute Vitamin D₃ oral rinse (50 paired specimens). Samples were analyzed in parallel by saliva RAT and rapid RT-PCR under blinded conditions. Results: The oral rinse converted 68% (17/25) of paired specimens from RAT-positive to RAT-negative, reducing antigen positivity from 54.2% to 32.0% ( Conclusions: Vitamin D₃ oral rinsing was associated with reduced detection by saliva-based SARS-CoV-2 RAT while RT-PCR results remained largely preserved. These findings suggest a previously under-recognized pre-analytical variable capable of altering saliva-based antigen detection.

Indexed as

pre-analytical interferencepublic health surveillancerapid antigen test (RAT)salivaSARS-CoV-2vitamin D oral rinse

Identifiers

PMID42745778
PMCPMC13574574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.