Evidence map›Paper›PMID 42745743›Full record

Observational studyFrontiers in cellular and infection microbiology2026

Predictors and outcomes of recurrent bloodstream infection in hematological malignancies: a multicenter real-world study.

Yishu Tang, Yuhan Yan, Kai Zhao, Qian Cheng, Liwen Wang, Yulian Xiao, Zheng Fang, Yajing Wei, Xin Li

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yishu TangDepartment of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yuhan YanDepartment of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Kai ZhaoDepartment of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qian ChengDepartment of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Liwen WangDepartment of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yulian XiaoDepartment of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zheng FangDepartment of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yajing WeiDepartment of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xin LiDepartment of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent bloodstream infection (RBSI) is a life-threatening complication in patients with hematological malignancies (HMs), yet the determinants of recurrence remain poorly defined. We aimed to characterize the incidence, outcomes, and time-specific predictors of RBSI in HMs, and further explored the prognostic factors of RBSI. We performed a real-world study involving HM patients with BSI from three academic teaching hospitals during January 2010 to August 2023. Clinical characteristics associated with RBSI were assessed at the initial BSI and during subsequent febrile episodes after apparent resolution of the initial infection. Among 1,153 patients with HMs and BSI, 173 (15.0%) developed RBSI, whose mortality increased progressively with recurrent episodes, from 10.7% to 19.0% after the first recurrence, and to 30.5% after the second recurrence (P<0.01). At the initial BSI, a Charlson Comorbidity Index (CCI) >3 was associated with subsequent recurrence. During later febrile episodes, CCI >3, prior antibiotic exposure, acute respiratory failure, and platelet count <10×10

Indexed as

BacteremiaHematologic NeoplasmsSepsisAdultAgedFemaleHumansIncidenceMaleMiddle AgedPrognosisRecurrenceRetrospective StudiesRisk FactorsCharlson comorbidity indexfebrile episodeshematological malignanciesmortalityrecurrent bloodstream infections

Identifiers

PMID42745743
PMCPMC13574583

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.