Evidence map›Paper›PMID 42745250›Full record

ArticleBMC oral health2026

Automated measurement of Little's Irregularity Index on intraoral photographs using a convolutional neural network.

Moritz Kanemeier, Tuna Ergün, Thomas Stamm, Claudius Middelberg, Jonas Q Schmid

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Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Moritz Kanemeier *Department of Orthodontics, University of Münster, Albert-Schweitzer-Campus 1, Gebäude W 30, 48149, Münster, Germany. kanemeier@uni-muenster.de.ORCID 0000-0002-4223-0010
Tuna Ergün *Department of Orthodontics, University of Münster, Albert-Schweitzer-Campus 1, Gebäude W 30, 48149, Münster, Germany.
Thomas StammDepartment of Orthodontics, University of Münster, Albert-Schweitzer-Campus 1, Gebäude W 30, 48149, Münster, Germany.
Claudius MiddelbergDepartment of Orthodontics, University of Münster, Albert-Schweitzer-Campus 1, Gebäude W 30, 48149, Münster, Germany.
Jonas Q SchmidDepartment of Orthodontics, University of Münster, Albert-Schweitzer-Campus 1, Gebäude W 30, 48149, Münster, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuantification of dental irregularities is essential for assessing case severity, evaluating treatment outcomes, and aiding early detection of fixed retainer failure. Measurements are typically performed on casts or digital scans, although manual measurement on intraoral photographs has been explored to enable remote monitoring. This study evaluated automated measurement of mandibular anterior irregularity on intraoral photographs using a deep learning model.

methodsA dataset of intraoral occlusal photographs annotated with contact points of mandibular anterior teeth was created to train a neural network model. Individual tooth displacements and Little's Irregularity Index (LII) were computed from these contact points. Annotation reliability was assessed using intraclass correlation coefficients, and agreement between model-derived and reference LII measurements was evaluated using Bland-Altman analysis on an independent test set. A supplementary, exploratory Bland-Altman analysis was performed at the tooth level. An a priori power analysis determined the required size of the test set, based on a predefined equivalence threshold of 2 mm for LII.

resultsThe model demonstrated precise localisation of contact points, with a mean radial error of 0.55 ± 0.22 mm. Tooth displacement and LII were predicted with mean absolute errors of 0.42 ± 0.32 mm and 1.37 ± 0.89 mm, respectively. For LII, Bland-Altman analysis revealed a significant bias of 1.07 mm, with limits of agreement ranging from -1.36 mm to 3.50 mm. The exploratory tooth-level analysis yielded a bias of 0.21 mm and descriptive limits of agreement ranging from -0.74 mm to 1.17 mm.

conclusionsThe neural network enables automated detection of mandibular anterior landmarks and estimation of LII from intraoral photographs. Since the limits of agreement were wider than the predefined equivalence threshold, the proposed model can currently only be recommended as a complementary tool.

Indexed as

Image Processing, Computer-AssistedMalocclusionNeural Networks, ComputerPhotography, DentalConvolutional Neural NetworksDeep LearningHumansReproducibility of ResultsArtificial intelligenceDeep learningMachine learningOrthodonticsPhotography, dentalTooth displacement

Identifiers

PMID42745250
PMCPMC13579978

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.