Evidence map›Paper›PMID 42745249›Full record

ArticleBMC ophthalmology2026

Does abnormal head posture aid in amblyopia prevention?

Masoud Khorrami-Nejad, Mohamad Reza Akbari, Babak Masoomian, Hassan Qahtan, Kimia Daneshvar, Arash Mirmohmmadsadeghi

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Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Masoud Khorrami-NejadTranslational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran. dr.khorraminejad@gmail.com.
Mohamad Reza AkbariTranslational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Babak MasoomianTranslational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Hassan QahtanDepartment of Optometry, School of Rehabilitation, Tehran University of Medical Sciences, Enghelab St., Tehran, Iran.
Kimia DaneshvarTranslational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Arash MirmohmmadsadeghiTranslational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the prevalence and severity of unilateral amblyopia in patients with ocular abnormal head posture (AHP) and to investigate whether the presence of compensatory head posturing provides protection against the development of amblyopia.

methodIn this retrospective cross-sectional study, the medical records of 1400 patients with various etiologies of AHP were reviewed. This cohort included individuals with congenital superior oblique palsy (SOP) (n = 758), Duane retraction syndrome (DRS) (n = 582), and Brown syndrome (n = 60), all of whom were candidates for surgical treatment at Farabi Eye Hospital, Iran from 2015 to 2022. Unilateral amblyopia was defined based on the presence of ≥ 2 Snellen line difference in CDVA and CDVA being worse than 0.1 logMAR in the amblyopic eye.

resultsThe mean ages of patients with congenital SOP, DRS, and Brown syndrome were 12.8 ± 12.9 years, 19.3 ± 11.9 years, and 9.0 ± 7.0 years, respectively. The prevalence of amblyopia among patients with congenital SOP, DRS, and Brown syndrome was 65 (8.6%), 117 (20.1%), and 11 (18.3%), respectively. In the DRS group, patients without AHP had a significantly higher prevalence of amblyopia (26.4%) compared to those with AHP (18.1%) (P = 0.039). However, in the congenital SOP and Brown syndrome groups, there was no significant difference in the prevalence of amblyopia between patients with and without AHP (P > 0.05). There were no significant differences in the horizontal and vertical angles of deviation in primary position between groups of patients with and without AHP or amblyopia across all three ocular pathologies (all P > 0.05).

conclusionThe high prevalence of unilateral amblyopia among patients with ocular AHP, despite the presence of compensatory head posturing, indicates that while AHP can aid in maintaining binocular vision, it does not guarantee complete protection against the development of amblyopia.

Indexed as

AmblyopiaHeadPostureAdolescentAdultChildChild, PreschoolCross-Sectional StudiesDuane Retraction SyndromeFemaleHumansIranMalePrevalenceRetrospective StudiesVisual AcuityAbnormal head postureAmblyopiaBrown syndromeDuane retraction syndromeSuperior oblique palsy

Identifiers

PMID42745249
PMCPMC13576275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.