ArticleAnnals of biomedical engineering2026
In Silico Modeling and Validation of Post-Dilation in TAVI Patients.
Article in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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17 authors.
Funding
Abstract
PURPOSE (STATING THE MAIN PURPOSES AND RESEARCH QUESTION): The purpose of this study is to develop and validate a balloon post-dilation model into patient-specific transcatheter aortic valve implantation (TAVI) simulations, addressing the current lack of numerical models capable of reproducing this procedural step.
methodsA finite element model of a True
resultsThe calibrated balloon model accurately reproduced experimental inflation behavior around the nominal working pressure, and post-dilation was simulated in all cases. Quantitative comparison with post-operative CTs demonstrated high predictive accuracy of the final stent configuration. The average percentage error in orifice area was 1.55 ± 1.26%, while eccentricity error at the left ventricular outflow tract level was 1.54 ± 1.08. Inclusion of post-dilation reduced prediction errors by 53% for orifice area and 80% for eccentricity.
conclusionThe integration of balloon post-dilation significantly improves the accuracy and clinical relevance of patient-specific TAVI simulations. Incorporating this step is essential to reliably predict final stent configuration and support the development of robust in silico tools for personalized TAVI planning and risk assessment.
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