Evidence map›Paper›PMID 42745061›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

An easy-to-use laryngostroboscopy index for unilateral vocal fold paralysis reflects voice quality.

Alexander Mainka, Dirk Mürbe, Mario Fleischer, Tadeus Nawka

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Alexander MainkaDepartment of Audiology and Phoniatrics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Berlin, Germany. alexander.mainka@charite.de.ORCID http://orcid.org/0000-0003-4415-2084
Dirk MürbeDepartment of Audiology and Phoniatrics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Berlin, Germany.ORCID http://orcid.org/0009-0005-0556-4213
Mario FleischerDepartment of Audiology and Phoniatrics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-6186-8298
Tadeus NawkaDepartment of Audiology and Phoniatrics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, Berlin, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0001-8103-8542

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo date, laryngostroboscopic parameters have been rarely used as outcome measures in clinical interventional studies, due tomethodological difficulties.

methodsWe applied a greatly reduced laryngostroboscopy evaluation protocol to an intervention study for unilateral vocal fold paralysis. Here,we investigate the correlation between the newly designed laryngostroboscopy index for unilateral vocal fold paralysis (LSI-UVFP) andan expert group's rating of voice quality. The LSI UVFP evaluates four key parameters closely related to voice production in UVFPpatients: (1) the vocal fold position, (2) the glottal gap during the closed phase, (3) atrophy of the paralysed vocal fold, and (4) themucosal wave. Each parameter is classified on a four-point ordinal scale: 0 for normal, 1 for mild, 2 for moderate, and 3 for severe. 52video recordings from 26 patients, before and after a voice improving surgery, were evaluated using the LSI-UVFP.

resultsThe index demonstrates good reliability, with an intra-class correlation coefficient of 0.80. In addition, LSI-UVFP was found to show asignificant correlation with an auditory perceptual rating of voice quality.

conclusionThus, rating of laryngostroboscopy by the LSI-UVFP is a valid method for documenting and comparing therapeutic outcomes ininterventional studies for symptomatic UVFP. Its usage enables a meaningful interpretation of videolaryngostroboscopic data withregard to voice quality.

Indexed as

Glottal gapLaryngostroboscopy evaluation protocolMucosal waveNumerical analysisValidationVocal fold paralysis

Identifiers

PMID42745061

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