Evidence map›Paper›PMID 42745029›Full record

ArticleAnalytical and bioanalytical chemistry2026

Long-time measurements of calcium release by dental resin-based composites using a liquid-contact calcium ion-selective electrode.

Paula Calli Falcoswki, Bruna Marin Fronza, Handially Dos Santos Vilela, Roberto Ruggiero Braga, Mauro Bertotti

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paula Calli FalcoswkiDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, 05508-000, Brazil.ORCID http://orcid.org/0000-0003-4136-5471
Bruna Marin FronzaDepartment of Restorative Dentistry, School of Dental Medicine, Albert Einstein Israelite Hospital, São Paulo, São Paulo, 05652-900, Brazil.ORCID http://orcid.org/0000-0002-8444-3225
Handially Dos Santos VilelaDepartment of Biomaterials and Oral Biology, School of Dentistry, University of São Paulo, São Paulo, 05508-000, Brazil.ORCID http://orcid.org/0000-0003-2696-9154
Roberto Ruggiero BragaDepartment of Biomaterials and Oral Biology, School of Dentistry, University of São Paulo, São Paulo, 05508-000, Brazil.ORCID http://orcid.org/0000-0002-6237-3924
Mauro BertottiDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, 05508-000, Brazil. mbertott@iq.usp.br.ORCID http://orcid.org/0000-0001-9566-7577

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/01701-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/12761-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/03665-2Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/00246-1
6 · The paper itself

Abstract

Liquid-contact ion-selective electrodes have been successfully applied in electrochemical analysis over the past 60 years and remain a highly reliable platform in modern analytical chemistry. Owing to their structural simplicity, low fabrication cost, and reproducible operational behavior, these sensors offer an attractive and robust alternative for real-time measurements when their key analytical parameters are thoroughly understood. In this study, we fabricated and characterized a micro calcium ion-selective electrode (micro-ISE) based on a commercial membrane cocktail containing the ETH-1001 ionophore. Critical operational parameters were systematically evaluated to tailor the microelectrode for localized sensing, including expected measurement error, background electrolyte influence, signal stability, memory effects, and accuracy. The microsensor was subsequently positioned 20 μm above dental composite samples designed for dentin remineralization with varying inorganic compositions (100% CaHPO

Indexed as

Calcium releaseDental restorationIon-selective electrodesLiquid-contact ion-selective electrodes

Identifiers

PMID42745029

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.