Evidence map›Paper›PMID 42744992›Full record

ArticleInternational orthopaedics2026

Long-term survivorship after medial unicompartmental knee arthroplasty: the influence of medical comorbidities and previous knee surgery.

Tosca Cerasoli, Eleonora Branzanti, Mirco Lo Presti, Antongiulio Favero, Stefano Fratini, Loredana Mavilla, Alberto Grassi, Stefano Zaffagnini, Giulio Maria Marcheggiani Muccioli

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Article in International orthopaedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors.

Tosca CerasoliDibinem, Bologna, Italy. tosca.cerasoli@ior.it.ORCID https://orcid.org/0000-0003-1111-5869
Eleonora BranzantiClinica II-Sport, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Mirco Lo PrestiClinica II-Sport, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Antongiulio FaveroDibinem, Bologna, Italy.ORCID https://orcid.org/0009-0000-3047-5793
Stefano FratiniRizzoli Argenta, Ferrara, Italy.
Loredana MavillaClinical Trial Center, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Alberto GrassiDibinem, Bologna, Italy.
Stefano ZaffagniniDibinem, Bologna, Italy.
Giulio Maria Marcheggiani MuccioliDibinem, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate long-term implant survivorship after medial unicompartmental knee arthroplasty (UKA) and determine whether medical comorbidities or previous ipsilateral knee surgery were associated with revision, complications, or clinical outcomes.

methodsThis retrospective cohort included 168 medial UKAs with a mean follow-up of 119.7 ± 29.3 months in the survivorship analysis. Revision of any prosthetic component was the endpoint for Kaplan-Meier analysis. A nested cohort of 76 knees underwent outpatient clinical evaluation; analyses of comorbidities, previous surgery, complications, and clinical outcomes were restricted to this cohort.

resultsEighteen revisions occurred. Implant survivorship was 100% at five years, 96% at seven years, 86% at ten years, and 78% at 15 years. In the 76-knee clinical cohort, 92.1% had at least one comorbidity and 54.0% had multimorbidity; no evaluated comorbidity category was significantly associated with revision or long-term clinical outcomes. Previous ipsilateral knee surgery was associated with a lower Knee Society clinical score (73.6 ± 14.1 vs 80.7 ± 12.5; p = 0.036) and a non-significantly higher rate of complication or revision (28.6% vs 8.1%; odds ratio 4.56; p = 0.054).

conclusionMedial UKA provided satisfactory long-term survivorship in a real-world cohort. No clear association was identified between the evaluated comorbidity categories and long-term outcomes, although small subgroups and the absence of severity measures preclude definitive conclusions. Previous ipsilateral knee surgery was associated with a lower objective clinical score and may identify knees requiring more cautious pre-operative counselling.

Indexed as

ComorbiditiesComplicationsMedial unicompartmental knee arthroplastyRevision rateSurvivorship

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.