ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
Associations between MoCA screening-positive cognitive impairment, anxiety, depression, and quality of life in patients with oral cancer: a cross-sectional study in China.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundCognitive impairment identified by screening tools is common among patients with oral cancer and may be associated with psychological distress and reduced quality of life. However, evidence regarding these associations in patients with oral cancer, particularly in Chinese populations, remains limited.
aimTo assess the prevalence of screening-positive cognitive impairment and examine its associations with anxiety, depression, and quality of life among Chinese patients with oral cancer.
methodsA cross-sectional study was conducted at a tertiary hospital in Changde, Hunan Province, China, from June 15 to July 15, 2023. Data were collected using an online questionnaire, including demographic and clinical characteristics and standardized instruments: the Montreal Cognitive Assessment (MoCA), Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), and the University of Washington Quality of Life Questionnaire (UW-QoL). Spearman correlation analysis and multivariable logistic regression were performed to explore factors associated with screening-positive cognitive impairment.
resultsA total of 567 participants were included. The mean MoCA score was 19.25 ± 6.49, and the education-adjusted mean score was 19.55 ± 6.37. Using a MoCA cut-off score of < 24, 67.40% of participants were classified as screening-positive for cognitive impairment. UW-QoL scores were negatively correlated with SAS scores (r = - 0.2009, p < 0.01) and SDS scores (r = - 0.2055, p < 0.01), and positively correlated with adjusted MoCA scores (r = 0.2027, p < 0.01). Multivariable logistic regression analysis showed that older age, higher anxiety scores, and higher depression scores were positively associated with screening-positive cognitive impairment, whereas higher UW-QoL scores were negatively associated with cognitive impairment (all p < 0.05).
conclusionScreening-positive cognitive impairment was common among patients with oral cancer in China and was associated with psychological distress and quality of life. These findings suggest the potential value of incorporating cognitive and psychological screening into routine clinical care for patients with oral cancer. Longitudinal studies are needed to further clarify the temporal relationships among cognitive impairment, psychological symptoms, and quality of life.
Indexed as
Identifiers
42744945What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.