Evidence map›Paper›PMID 42744811›Full record

ArticleNature communications2026

scE

Hegang Chen, Yuyin Lu, Yifan Zhao, Zhiming Dai, Fu Lee Wang, Qing Li, Yanghui Rao, Yue Li

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hegang ChenSchool of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Yuyin LuSchool of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Yifan ZhaoDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-4829-1428
Zhiming DaiSchool of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0001-6211-6568
Fu Lee WangSchool of Science and Technology, Hong Kong Metropolitan University, Hong Kong, China.
Qing LiDepartment of Computing, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0003-3370-471X
Yanghui RaoSchool of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, China. raoyangh@mail.sysu.edu.cn.ORCID 0000-0003-1610-9599
Yue LiSchool of Computer Science, McGill University, Montreal, QC, Canada. yueli@cs.mcgill.ca.ORCID 0000-0003-3844-4865

Funding

National Natural Science Foundation of China (National Science Foundation of China) 62372483
6 · The paper itself

Abstract

Single-cell RNA sequencing reveals cellular heterogeneity, yet computational methods struggle to balance performance with biological interpretability. Embedded topic models provide interpretable cell representations, but may learn overly similar topics, resulting in redundancy and incomplete capture of biological variation. Single-cell foundation models create opportunities to harness external biological knowledge for guiding model embeddings. Here, we present scE

Indexed as

Computational BiologySingle-Cell AnalysisAlgorithmsCluster AnalysisClustering AlgorithmsHumansLeukocytes, MononuclearMelanomaSequence Analysis, RNASingle-Cell Gene Expression Analysis

Identifiers

PMID42744811
PMCPMC13578707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.