Evidence map›Paper›PMID 42744803›Full record

ArticleNature communications2026

Global genomic surveillance uncovers emergence and spatiotemporal patterns of World Health Organization priority antibiotic resistance in invasive Salmonella.

Yuhang Pei, Ziru Yang, Xiaolu Pang, Wufuer Xiayidan, Meilian Huang, Jinhua Meng, Yufeng Qiu, Mingliu Wang, Hongxia Yang, Chunmei Jing and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Yuhang Pei *International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Ziru Yang *International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Xiaolu PangDepartment of Clinical Laboratory, The Fourth People's Hospital of Nanning, Nanning, China.
Wufuer XiayidanDepartment of Microbiology, Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi, China.
Meilian HuangDepartment of Laboratory Medicine, Children's Hospital of Fudan University (Xiamen Branch), Xiamen Children's Hospital, Xiamen, China.
Jinhua MengCenter of Clinical Medical Laboratory, Shanxi Children's Hospital, Taiyuan, China.
Yufeng QiuFujian Center for Disease Control and Prevention, Fujian Provincial Key Laboratory of Zoonosis Disease Research, Fuzhou, China.
Mingliu WangGuangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning, China.
Hongxia YangShanxi Center for Disease Control and Prevention, Taiyuan, China.
Chunmei JingChildren's Hospital of Chongqing Medical University, Chongqing, China.
Mei ZengDepartment of Infectious Diseases, Children's Hospital of Fudan University, Shanghai, China.
Yue LiuDivision of Pathogen Testing and Analysis, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Wenqing WangDepartment of Microbiology, Shanghai Pudong New Area Center for Disease Control and Prevention (Shanghai Pudong New Area Health Supervision Institute), Shanghai, China.
Yibin ZhouDepartment of Infectious Disease Control, Center for Disease Control and Prevention of Minhang District, Shanghai, China.
Sufang MaBeijing Key Laboratory of Antimicrobial-Resistant Pathogen Microbiology and AI-Empowered Containment, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Na LyuBeijing Key Laboratory of Antimicrobial-Resistant Pathogen Microbiology and AI-Empowered Containment, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Mengqi QuInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Chaochao ZhaoInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Jiangtao WangInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Jiale ChenInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Baoli ZhuBeijing Key Laboratory of Antimicrobial-Resistant Pathogen Microbiology and AI-Empowered Containment, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0001-5326-9503
George F GaoBeijing Key Laboratory of Antimicrobial-Resistant Pathogen Microbiology and AI-Empowered Containment, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0002-3869-615X
Xuebin XuDivision of Pathogen Testing and Analysis, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China. xuxuebin@scdc.sh.cn.ORCID 0000-0002-1986-6539
Yanan WangInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China. wangyanan1001@henau.edu.cn.ORCID 0000-0002-7461-2195

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) in invasive Salmonella infections remains a global public health concern, and enhanced high-quality genomic surveillance is essential to inform guidelines and policies. Here, we aimed to describe clinically key antibiotic resistance trends in invasive Salmonella infections using 7691 isolates derived from national surveillance and publicly available datasets between 1954 and 2024. 29 (37.7%) of 77 countries identified at least one isolate with resistance or decreased susceptibility to ciprofloxacin, 25 (32.5%) and 29 (37.7%) countries resistance or decreased susceptibility to ceftriaxone and cefixime, 8 (10.4%) countries resistance to azithromycin, 15 (19.5%) countries resistance to fosfomycin, 10 (13.0%) countries resistance to colistin. Overall, 7.39% of 7691 isolates were resistant or decreased susceptibility to ciprofloxacin, 7.91% reported resistance or decreased susceptibility to 3GCs, 4.23% reported resistance to fosfomycin, and 0.79% reported resistance to azithromycin. Globally, azithromycin resistance is increasing, as is resistance or decreased susceptibility to ciprofloxacin, 3GCs, and 4GCs. However, surveillance levels remain inadequate in African and South American regions. We generated a global map of clinically key antibiotic resistance genes in invasive Salmonella infections worldwide. This retrospective, global, longitudinal genomic epidemiology study on invasive Salmonella provides evidence-based data for clinical guidelines, genomic surveillance, AMR control, and public health policies.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialDrug Resistance, Multiple, BacterialSalmonellaSalmonella InfectionsAzithromycinCiprofloxacinGenome, BacterialGenomicsGlobal HealthHumansMicrobial Sensitivity TestsSpatio-Temporal AnalysisThird Generation CephalosporinsWorld Health OrganizationAnti-Bacterial AgentsAzithromycinCiprofloxacinThird Generation Cephalosporins

Identifiers

PMID42744803
PMCPMC13578455

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.