Evidence map›Paper›PMID 42744792›Full record

ArticleNature communications2026

Assistive algorithms influence neural representations in motor brain-computer interfaces.

Pavithra Rajeswaran, Alexandre Payeur, Guillaume Lajoie, Amy L Orsborn

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pavithra RajeswaranDepartment of Bioengineering, University of Washington, Seattle, WA, USA.ORCID 0000-0002-3692-215X
Alexandre PayeurDepartment of Mathematics and Statistics, Université de Montréal, Montréal, QC, Canada.ORCID 0000-0002-2437-8249
Guillaume Lajoie *Department of Mathematics and Statistics, Université de Montréal, Montréal, QC, Canada. g.lajoie@umontreal.ca.ORCID 0000-0003-2730-7291
Amy L Orsborn *Department of Bioengineering, University of Washington, Seattle, WA, USA. aorsborn@uw.edu.ORCID 0000-0003-4131-5781

Funding

Interdisciplinary Engineering Career Development Center in Movement and Rehabilitation SciencesK12HD073945 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P, REINKENSMEYER, DAVID JAY · 2012 to 2021
$7.9M
Optimizing co-adaptation in motor BCIs by uncovering brain-decoder interactionsR01NS134634 · NINDS · UNIVERSITY OF WASHINGTON · PI Amy L Orsborn · 2023 to 2026
$2.9M
Canada First Research Excellence Fund (Fonds d'excellence en recherche Apog&ée Canada) IVADO postdoctoral fellowshipCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada (NSERC Canadian Network for Research and Innovation in Machining Technology) RGPIN-2018-04821National Science Foundation (NSF) Accelnet INBIC fellowshipNICHD NIH HHS K12 HD073945NINDS NIH HHS R01 NS134634Simons Foundation 898220U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) K12HD073945U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS134634
6 · The paper itself

Abstract

Task errors are used to learn and refine motor skills. We investigated how task assistance influences learned neural representations using Brain-Computer Interfaces (BCIs), which map neural activity into movement via a decoder. We analyzed motor cortex activity as monkeys practiced BCI with a decoder that adapted to improve or maintain performance over days. Over time, task-relevant information became concentrated in fewer neurons, unlike with fixed decoders. At the population level, task information also became largely confined to a few neural modes that accounted for a small fraction of the population variance. A neural network model suggests the adaptive decoders directly contribute to forming these more compact neural representations. Our findings suggest that assistive decoders manipulate error information used for long-term learning computations like credit assignment, which may explain the altered neural representations and inform real-world BCI design.

Indexed as

AlgorithmsBrain-Computer InterfacesMotor CortexAnimalsLearningMacaca mulattaMaleModels, NeurologicalMovementNeural Networks, ComputerNeurons

Identifiers

PMID42744792
PMCPMC13578456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.