Evidence map›Paper›PMID 42744384›Full record

ArticleBMJ open2026

Work-related stress and consumption of psychoactive substances and medications among early childhood professionals (TraPsyCOL): study protocol for a cross-sectional study.

Walaa Khazaal, Stéphane Onnée, Roomila Naeck, Séverine Morisset-Lopez, Patrick Baril, Olivier Vernay, Raphaël Serreau

Abstract read
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Walaa KhazaalCentre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Orléans, France Walaa.khazaal@cnrs-orleans.fr.ORCID http://orcid.org/0009-0007-9817-0292
Stéphane OnnéeVALLOREM, UR6296-VAL de Loire REcherche en Management, Université d'Orléans, Orléans, France.
Roomila NaeckNovatech SA, La Ciotat, France.
Séverine Morisset-LopezCentre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Orléans, France.ORCID http://orcid.org/0000-0002-9930-7824
Patrick BarilCentre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Orléans, France.ORCID http://orcid.org/0000-0001-8290-9899
Olivier VernayCommunauté de Communes des Terres du Val de Loire, Meung-sur-Loire, France.
Raphaël SerreauCentre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Orléans, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWork-related stress is a major public health concern affecting workers across various sectors. It may be associated with increased psychoactive substance use, primarily alcohol, tobacco and cannabis as well as psychoactive medications, which may represent coping mechanisms in response to occupational stress. Work-related stress is also associated with adverse outcomes such as burnout, depression, anxiety and sleep-related problems (excessive daytime sleepiness).This study focuses on three groups of early childhood professionals in France: 'ATSEMs' (preschool classroom assistants who support teachers, help maintain the classroom environment and work exclusively in nursery schools), 'animateurs' (staff supervising educational and extracurricular activities outside school hours) and 'agents d'entretien' (cleaning and maintenance staff) working in nursery and elementary schools, the latter two work in both nursery and elementary schools. These professionals play a crucial role in the education, care and well-being of children but are exposed to high levels of occupational stress due to the emotionally demanding nature of their work, which may increase the risk of substance use, burnout, depression, anxiety and excessive daytime sleepiness. We hypothesise that professionals exposed to job strain (stressed work) will have higher odds of psychoactive substance and medication use, higher levels of substance-related risk or dependence and higher odds of burnout, symptoms of anxiety and depression and sleep-related problems compared with those not exposed to job strain. METHODS AND ANALYSIS: This cross-sectional epidemiological study is being conducted among early childhood professionals working in nursery and elementary schools in participating territories across the Axe ligérien in France. The study aims to investigate the association between work-related stress and the use of psychoactive substances and medications and to evaluate the associated levels of substance-related risk or dependence among 'ATSEMs', 'animateurs' and 'agents d'entretien', as well as the association between work-related stress and burnout, depression, anxiety and excessive daytime sleepiness. Data are being collected anonymously using a self-administered online questionnaire, accessible via a QR code displayed on study posters placed in staff rooms and other shared areas in participating schools as well as on flyers distributed among staff containing the same study information and QR code. The QR code also provides access to an information sheet explaining that the study complies with ethical guidelines and that proceeding to the questionnaire indicates non-objection to participation. A sample size of 234 participants was estimated using BiostaTGV. Descriptive analyses will be conducted. Associations between work-related stress, operationalised as job strain and the study outcomes will be examined using Pearson's χ ETHICS AND DISSEMINATION: Ethical approval for this study was obtained from the Ethics Committee of the Centre Hospitalier Universitaire d'Orléans (assigned reference number: CERO 2511-02). Participation is voluntary and anonymous. The findings of the study will be disseminated through peer-reviewed, open-access publications and scientific conferences.

Indexed as

Occupational StressPsychotropic DrugsSchool TeachersSubstance-Related DisordersAdultAnxietyBurnout, ProfessionalCross-Sectional StudiesDepressionFemaleFranceHumansMaleResearch DesignSchoolsSurveys and QuestionnairesPsychotropic DrugsBurnoutMENTAL HEALTHOccupational StressSubstance misuse

Identifiers

PMID42744384
PMCPMC13583687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.