Evidence map›Paper›PMID 42743904›Full record

ReviewJACC. Advances2026

Evolving Evidence-Driven Strategies in Cardiogenic Shock Management.

Anju Bhardwaj, Dustin Hillerson, Nikhil Narang, Megan N Pelter, Anjan Sinha, Maya Guglin

Abstract readReview
In one paragraph

Review in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anju BhardwajUniversity of Virginia, Charlottesville, Virginia, USA. Electronic address: anju.bhardwaj@uvahealth.org.
Dustin HillersonMayo Clinic, Rochester, Minnesota, USA.
Nikhil NarangUniversity of Chicago, Chicago, Illinois, USA.
Megan N PelterLoma Linda University School of Medicine, Loma Linda, California, USA.
Anjan SinhaIndiana University School of Medicine, Indianapolis, Indiana, USA.
Maya GuglinRutgers University, New Brunswick, New Jersey, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although existing guidelines and expert consensus documents provide a general framework for management of cardiogenic shock (CS), a substantial body of evidence has yet emerged which has not been fully incorporated into current recommendations. This State-of-the Art review synthesizes both established and recent literature to provide an updated perspective on contemporary CS management. We review randomized controlled trials and key observational studies evaluating invasive hemodynamic monitoring, pharmacologic therapies, temporary mechanical circulatory support, and structural and valvular interventions. We critically appraise trial design, patient heterogeneity, and methodological limitations that influence interpretation and clinical applicability. Finally, we highlight persistent gaps and ongoing trials that aim to refine risk stratification and treatment strategies. This review provides a comprehensive, up-to-date synthesis of the CS literature and outlines key directions for future research and clinical practice.

Indexed as

cardiogenic shockclinical guidelinesmechanical circulatory support

Identifiers

PMID42743904
PMCPMC13595213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.