Evidence map›Paper›PMID 42743837›Full record

ArticleDrug and alcohol dependence2026

Prospective and cross-sectional associations of neighborhood socioeconomic disadvantage with drinking and heavy drinking in mid-adulthood in a US national cohort.

Wendy S Slutske, Timothy B Baker, Jason D Boardman, Thomas M Piasecki

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Article in Drug and alcohol dependence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Wendy S SlutskeDepartment of Family Medicine and Community Health, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA; Center for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: slutske@wisc.edu.
Timothy B BakerCenter for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Jason D BoardmanDepartment of Sociology and Institute of Behavioral Science, University of Colorado, Boulder, CO, USA.
Thomas M PiaseckiCenter for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VII Core ProjectU01AG071448 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT A HUMMER · 2021 to 2026
$40.2M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Cognition and Early Risk Factors for Dementia ProjectU01AG071450 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AIELLO, ALLISON E, HUMMER, ROBERT A · 2021 to 2025
$16.2M
Genes, neighborhoods, and alcohol misuse from adolescence to mid-adulthood in the Add Health studyR01AA031773 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI WENDY S SLUTSKE · 2024 to 2026
$945k
NIAAA NIH HHS R01 AA031773NIA NIH HHS U01 AG071448NIA NIH HHS U01 AG071450NICHD NIH HHS P01 HD031921
6 · The paper itself

Abstract

backgroundUnderstanding how neighborhood socioeconomic disadvantage contributes to risk for alcohol use and misuse has important implications for prevention and intervention.

methodsData were from the National Longitudinal Survey of Adolescent to Adult Health. Past-month quantity-frequency of alcohol use and heavy drinking in mid-adulthood (ages 33-43) were prospectively and cross-sectionally predicted from neighborhood socioeconomic disadvantage measured in adolescence (ages 12-21) and in mid-adulthood (ages 33-43). Differences in exposure and vulnerability to neighborhood disadvantage by race/ethnicity, sex, and socioeconomic status were also examined.

resultsThere was a significant prospective, but not cross-sectional, association between greater neighborhood disadvantage and reduced alcohol use in mid-adulthood. Each additional standard deviation of disadvantage in adolescence was associated with a 14% (p < .001) decrease in the number of drinks (about three fewer drinks) and 20% (p < .001) reduced odds of heavy drinking in the past month in mid-adulthood and this was not affected by the neighborhood to which one was exposed in mid-adulthood. This relation was significantly moderated by race/ethnicity wherein the association between neighborhood disadvantage in adolescence and less alcohol use in mid-adulthood was significant among White but not among Hispanic, Black, or Asian/Pacific Islander individuals.

conclusionsThese results suggest that prevention and intervention efforts should focus on exposure to neighborhood disadvantage in adolescence. Research is needed that can identify the mechanisms underlying the effect of neighborhood disadvantage on alcohol outcomes, especially mechanisms specific to race/ethnicity subgroups, accounts for exposure versus vulnerability, and can disentangle causal associations from differential selection into disadvantaged neighborhoods.

Indexed as

AdolescenceAlcohol quantity-frequencyExposure versus vulnerabilityHeavy drinkingMid-adulthoodNational Longitudinal Study of Adolescent to Adult HealthNeighborhood socioeconomic disadvantage

Identifiers

PMID42743837
PMCPMC13625655

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.